smaller steps here
#retatrutide 2025-04-26
Saturday45 messages9 participantstimes are UTC
Highlights from this day
- eighteen_months — genuine question GI was about the same as tirzepatide for me, the difference was how fast it arrived 17:53
- quiet_head_qi — coming back to this anyone compared their VendorInvestigate purity across two different SSA lots 18:27
- swab_dry_first — anyone stayed at 1.7 for months rather than climbing 18:49
- surpass_two — blood pressure stayed flat for me while heart rate moved, which i didnt expect, anyway 19:43
while im here the half life supports weekly dosing and thats what ive done from the start
phase 2 only
how do people square the research use only framing with logging their own use
did the phase 2 plateau or was it still moving at the end
stopped for 1 months and restarted at half my old dose, the ramp was easier second time
i went up too fast, got a fortnight of nothing but nausea, and dropped back two steps
anyone gone above 0.5 and what changed
research use only
i said 5 months ago that my heart rate had settled and it has stayed settled since
people insist on small steps because the side effects arrive faster than on the other two
right so is TRIUMPH the phase 3 programme
genuine question GI was about the same as tirzepatide for me, the difference was how fast it arrived
no idea whether the heart rate settles for everyone, mine did and one log isnt data, ymmv
low and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom
the glucagon arm is the mechanistic story for extra energy expenditure and its still a story to me
glucagon is the new bit
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anyone reconstituting 40 vials to 10 so the steps come out smaller
held at 2.4 for 26 months and it never plateaued for me, which i cant explain
right so came off at 21 weeks because my resting rate stayed elevated and i didnt like it
*week 11 not week 8
mine went up too
[edited]stepping in 1.7 increments instead of doubling is the only thing i would change if i started again, someone check my working
reconstituted the 15 vial to 2mg/ml specifically so i could take 5 without measuring crumbs
coming back to this anyone compared their VendorInvestigate purity across two different SSA lots
nobody should read my log as a plan, im recording what i did and thats all it is
does the glucagon arm explain the heart rate or is that unrelated
watching my heart rate
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phase 2 was still trending at the end which is why the phase 3 readout matters more than usual
anyone stayed at 1.7 for months rather than climbing
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is the phase 2 dosing anywhere near what people here run
low and slow
[edited]my resting rate went up 7 bpm in the first month and came back most of the way by month 9
im at 2.4 and the appetite effect is stronger than i expected, normal
On this day 7 years ago this channel logged 107 messages.
genuine question is the glucagon arm what people mean by the energy expenditure thing
back after 1 months, has anything actually been published since
whats the half life like, is it weekly the same way
blood pressure stayed flat for me while heart rate moved, which i didnt expect, anyway
TRIUMPH is the phase 3 programme, thats the name to search rather than the molecule, take that with a pinch of salt
logging rhr daily
sat at 2 for 5 months rather than climbing and it kept working, so i never went up
no long term data
how long before people saw the first change at 1.7
follow up anyone tracking blood pressure alongside the heart rate
cant feel it honestly