vialroom

#retatrutide 2025-04-25

Friday14 messages4 participantstimes are UTC
Highlights from this day
  • triple_ag_tom — sorry to jump in my resting rate went up 8 bpm in the first month and came back most of the way by month 19 16:07
  • per_mg_pete — unrelated but lost 15kg over 7 months at doses well under what the trials used, take that with a pinch of salt 16:22
  • still_here_2024 — anyone stayed at 15 for months rather than climbing 16:52
TA

i said 2 months ago that my heart rate had settled and it has stayed settled since

sorry to jump in my resting rate went up 8 bpm in the first month and came back most of the way by month 19

whats a sensible starting point, im seeing everything from 0.5 to 2

settled by month three

PM

unrelated but lost 15kg over 7 months at doses well under what the trials used, take that with a pinch of salt

cant feel it honestly

TA

there is no long term safety data, phase 2 and an ongoing phase 3 programme is what exists

SH

stepping in 2 increments instead of doubling is the only thing i would change if i started again

is TRIUMPH the phase 3 programme

NA

triple agonist, GLP-1 and GIP and glucagon. the glucagon arm is the part with no long history

SH

anyone stayed at 15 for months rather than climbing

Cited study
Triple–Hormone-Receptor Agonist Retatrutide for Obesity — A Phase 2 Trial
New England Journal of Medicine · 2023
48 weeks, dose-ranging. A Phase 2 result is not a safety record.
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