vialroom

#retatrutide 2024-11-11

Monday15 messages5 participantstimes are UTC
Highlights from this day
  • maintenance_mo — quick one energy expenditure isnt something i could feel, though my sleep tracker disagreed with me, i think 07:52
  • oasis_ola — i said 8 months ago that my heart rate had settled and it has stayed settled since held at 2.4 for 16 months and it never plateaued for me, which i cant explain 08:02
  • two_ml_two — there is no long term safety data, phase 2 and an ongoing phase 3 programme is what exists 08:03
  • oasis_ola — Janoshik came back 99.4 on one lot and 98.6 on the next from the same KP, both fine, not advice obviously 08:07
  • meal_prep_mick — anyone compared their Janoshik purity across two different HJ lots 08:41
MM

quick one energy expenditure isnt something i could feel, though my sleep tracker disagreed with me, i think

❤️16
OO

watching my heart rate

Cited study
Triple–Hormone-Receptor Agonist Retatrutide for Obesity — A Phase 2 Trial
New England Journal of Medicine · 2023
48 weeks, dose-ranging. A Phase 2 result is not a safety record.

did the phase 2 plateau or was it still moving at the end

i said 8 months ago that my heart rate had settled and it has stayed settled since
held at 2.4 for 16 months and it never plateaued for me, which i cant explain

🤝6🎉11💀6
TM

there is no long term safety data, phase 2 and an ongoing phase 3 programme is what exists

baseline  58
wk 2      61
wk 4      64
wk 6      67
wk 8      66
wk 10     65   (held dose from wk 7)
MP

held at 12 for 9 months and it never plateaued for me, which i cant explain

OO

Janoshik came back 99.4 on one lot and 98.6 on the next from the same KP, both fine, not advice obviously

baseline  58
wk 2      61
wk 4      64
wk 6      67
wk 8      66
wk 10     65   (held dose from wk 7)

*Janoshik not the other one

MP

the honest position is this has less human evidence behind it than anything else discussed here

MM

ok so blood pressure stayed flat for me while heart rate moved, which i didnt expect, for what its worth

TM

right so i was wrong to call the heart rate a non issue last year, enough people logged it that i changed my mind

*Janoshik not the other one