did the phase 2 result actually come in higher than the tirzepatide numbers
#retatrutide 2024-10-22
Tuesday22 messages2 participantstimes are UTC
Highlights from this day
logging rhr daily
unrelated but appetite suppression at 2.4 was stronger than my tirzepatide experience at a comparable point
triple agonist, GLP-1 and GIP and glucagon. the glucagon arm is the part with no long history, we shall see
how long before people saw the first change at 2.4
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i went up too fast, got a fortnight of nothing but nausea, and dropped back two steps
GI was about the same as tirzepatide for me, the difference was how fast it arrived
stopped for 5 months and restarted at half my old dose, the ramp was easier second time, i think
phase 2 only
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anyone compared their PeptideMeter purity across two different HJ lots
low and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom
lost 21kg over 8 months at doses well under what the trials used
*Janoshik not the other one
reconstituted the 10 vial to 4mg/ml specifically so i could take 2 without measuring crumbs
TRIUMPH is the phase 3 programme, thats the name to search rather than the molecule
TRIUMPH is phase 3
glucagon is the new bit
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i was wrong to call the heart rate a non issue last year, enough people logged it that i changed my mind
unrelated but phase 2 was still trending at the end which is why the phase 3 readout matters more than usual
blood pressure stayed flat for me while heart rate moved, which i didnt expect, i think
research use only