vialroom

#reconstitution 2025-04-13

Sunday53 messages12 participantstimes are UTC
Highlights from this day
  • appetite_back — temperature of the diluent does not matter. how fast you push it in does 17:50
  • coa_or_cope — aim the diluent at the glass wall, not at the powder. it goes in gentler 17:52
  • dorm_fridge — i have never once regretted using a rounder number and a slightly bigger volume 18:58
  • gradient_greg — weighing the vial before you reconstitute is the only way to catch an underfill 19:24
  • VialBot — Batch lookup H-2814: 7 independent reports on file, earliest 2024-09-24. 21:15
VB

Purity check: no report on file for lot B-0114. Nothing logged either way.

AB

can i add more bac water later to a vial ive already reconstituted

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i write the mg/ml on the vial with a sharpie the moment i reconstitute it

AB

temperature of the diluent does not matter. how fast you push it in does

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CO

aim the diluent at the glass wall, not at the powder. it goes in gentler

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lyophilised powder is far more robust than people think. it is the solution that is fragile

how long after reconstituting before its actually dissolved

CO

yep 10 units

10mg vial
  + 1.0ml  -> 10.0 mg/ml   0.5mg =  5u   1mg = 10u
  + 2.0ml  ->  5.0 mg/ml   0.5mg = 10u   1mg = 20u
  + 2.5ml  ->  4.0 mg/ml   0.5mg = 12.5u (dont)
  + 5.0ml  ->  2.0 mg/ml   0.5mg = 25u   1mg = 50u

label the vial

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VB

On this day 9 years ago this channel logged 140 messages.

GG

if the powder is on the stopper, tap it down before you add anything. it will still dissolve either way

DF

do not add more bac water to an already reconstituted vial, you have lost track of the concentration

DF

while im here i use bac water even for a single-use vial because it stings less, which is not the reason it exists

[edited]

thats 5mg/ml

i have never once regretted using a rounder number and a slightly bigger volume

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GG

i swirl for about thirty seconds and then leave it. never had one fail to dissolve

does it matter if i inject the bac water straight at the powder

the meniscus thing is real. read it at eye level or you are guessing by a unit either way, i have it written down somewhere
update from 16 months ago: switched to a single concentration and have not miscalculated since

weighing the vial before you reconstitute is the only way to catch an underfill

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CO

my rule is one concentration for everything so i never have to think about it at 7am

CO

20mg in 2ml is 10mg/ml. 1mg is 10 units, 2mg is 20 units, easy

CO

while im here took me a year to stop over-diluting. the measurement error at 4 units is worse than the convenience, from memory

thats the vacuum

5mg in 2ml gives 2.5mg/ml, 0.25mg is 10 units. good for a starting dose

peptidemeter-summary-sg-1177.pdf
2 pages · 192 KB · not retained in the public archive

thats fine

EE

bac water or sterile water for something im going into weekly for 6 weeks

if you cannot read the mark confidently, your volume is too small. redo it at a lower concentration

CH

one unit is 0.01ml. 100 units is 1ml. everything else in this channel follows from that

AB

my 10mg vial weighed 11.4g on the jewellery scale, is that wrong
the last few units are a real loss. i accept it rather than tilting the vial and drawing air

TE

for the archive 30mg in 3ml is 10mg/ml, so 5mg is 50 units. half the barrel, feels like a lot but its right, i could be wrong

TE

the vacuum will pull it in. let it. fighting it is how you get a face full of aerosol

PC

bacteriostatic water for anything multi-use. sterile water has no preservative in it at all

VB

Batch lookup H-2814: 7 independent reports on file, earliest 2024-09-24.

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CO

is it worth buying a 3ml syringe for the diluent or is the insulin one fine

22:39chlorhex pinned a message to this channel