vialroom

#reconstitution 2025-04-11

Friday43 messages9 participantstimes are UTC
Highlights from this day
  • karl_fischer — i have never once regretted using a rounder number and a slightly bigger volume 22:07
  • VialBot — Assay note: BCH lot F-1330 reported at 98.6% of label content. 22:31
  • septum_sal — dead space in a standard insulin syringe hub is small but it is not nothing over a month 22:53
  • vienna_vial — 30mg in 3ml is 10mg/ml, so 5mg is 50 units. half the barrel, feels like a lot but its right, happy to be corrected 22:55
AA

i keep a spare vial of bac water in the fridge purely so i never rush the maths

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update from 15 months ago: switched to a single concentration and have not miscalculated since

NW

if you cannot read the mark confidently, your volume is too small. redo it at a lower concentration

temperature of the diluent does not matter. how fast you push it in does

KF

i have never once regretted using a rounder number and a slightly bigger volume

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SS

write the date on

fridge-temps.csv
880 rows · not retained in the public archive
KF

a 3ml syringe for the diluent and a u100 for the dose is the setup most people here end up with

follow up anyone worked out a recon volume that puts 2.4mg on a round unit mark

20mg in 2ml is 10mg/ml. 1mg is 10 units, 2mg is 20 units, easy

MG

if the powder is on the stopper, tap it down before you add anything. it will still dissolve either way

pick the volume so your dose is a whole number of units. thats the entire trick

KF

is it worth buying a 3ml syringe for the diluent or is the insulin one fine

PP

whats the smallest volume you would trust yourself to measure on a u100

lyophilised powder is far more robust than people think. it is the solution that is fragile

VB

Assay note: BCH lot F-1330 reported at 98.6% of label content.

one unit is 0.01ml

one unit is 0.01ml. 100 units is 1ml. everything else in this channel follows from that, we shall see

label the date too. you will not remember which vial is which by week 11

my rule is one concentration for everything so i never have to think about it at 7am

weigh it first

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SS

quick one does benzyl alcohol matter if im finishing the vial in one go

dead space in a standard insulin syringe hub is small but it is not nothing over a month

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VV

30mg in 3ml is 10mg/ml, so 5mg is 50 units. half the barrel, feels like a lot but its right, happy to be corrected

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SS

15mg in 3ml is 5mg/ml. same numbers as 10 in 2, just more of it
it should be completely clear with no floaters. cloudy means stop

VV

bac water or sterile water for something im going into weekly for 9 weeks

anyone else find the 20mg vials harder to get fully dissolved than the small ones

AA

im getting bubbles in the barrel every single time, what am i doing wrong

5mg in 2ml gives 2.5mg/ml, 0.25mg is 10 units. good for a starting dose, i have it written down somewhere

how long after reconstituting before its actually dissolved

VV

weighing the vial before you reconstitute is the only way to catch an underfill

AA

sanity check my maths before i pin myself with something stupid

AA

coming back after 6 months, has the pinned recon volume advice changed

VV

my 10mg vial weighed 11.4g on the jewellery scale, is that wrong

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