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#oral-glp1 2025-12-08

Monday19 messages5 participantstimes are UTC
Highlights from this day
  • split_the_cost — changed my mind on the plain water rule after reading how SNAC works, its not a formality 20:38
  • split_the_cost — ok so i said 3 months ago that my oral results were random, they got consistent once i fixed the water, ask me again in a month 21:15
  • VialBot — Channel stats, last 30 days: 135 messages from 45 members. 21:18
ST

lost 8kg over 14 months on oral, slower than my injectable stretch, i stuck with it anyway

ST

ok so splitting a dose made the absorption problem worse rather than better in my own log

TW

sorry to jump in orforglipron is a small molecule rather than a peptide, which is why the fasting conditions differ

ST

changed my mind on the plain water rule after reading how SNAC works, its not a formality

Cited study
Oral Semaglutide 50 mg in Adults with Overweight or Obesity (OASIS 1)
The Lancet · 2023
The high-dose oral. Absorption rules matter enormously here.

anyone tracking whether their oral results line up week to week

while im here the 30 minutes starts when you swallow it, and i set a timer because i cannot be trusted

SNAC does the work

EM

roughly one percent gets absorbed, which is why the tablet strength looks nothing like an injectable dose

EM

sorry to jump in oral was easier on my gut than injecting at what felt like a similar effect, which surprised me

took mine with breakfast once by accident and that week was a write off

big mg small dose

ST

ok so i said 3 months ago that my oral results were random, they got consistent once i fixed the water, ask me again in a month

VB

Channel stats, last 30 days: 135 messages from 45 members.