took 25 weeks before i saw anything on oral, roughly twice what the injection took me
#oral-glp1 2025-07-23
Wednesday22 messages6 participantstimes are UTC
Highlights from this day
- tokyo_taper — i do 6am with water and eat at 7, thats been my routine for 8 months 20:29
- glasgow_vial — genuine question orforglipron is a small molecule rather than a peptide, which is why the fasting conditions differ i do 6am with water and eat at 7, thats been my… 20:31
- rotate_the_site — one percent is the number people quote and the spread around it is the actual story 20:46
- rotate_the_site — why is the oral dose in mg so much bigger than the injectable one 21:35
the non peptide orals are the interesting part of this channel now, not oral semaglutide, thats just me
SNAC raises the local pH and protects it long enough to cross, thats its whole job
plain water only, about half a glass, then nothing for 30 minutes. i follow it exactly
lost 12kg over 19 months on oral, slower than my injectable stretch, i stuck with it anyway, not advice obviously
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right so back after 23 months, has anything changed on the oral side
oral was easier on my gut than injecting at what felt like a similar effect, which surprised me
i do 6am with water and eat at 7, thats been my routine for 8 months
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technique probably
genuine question orforglipron is a small molecule rather than a peptide, which is why the fasting conditions differ
i do 6am with water and eat at 7, thats been my routine for 5 months
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one percent is the number people quote and the spread around it is the actual story
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slightly off topic but is the absorption variability why the oral doses look so high
unrelated but the non peptide agents dose daily without the water ritual, thats the practical difference
coming back to this i keep the tablet by the kettle so i take it before i think about food
i was wrong about the water amount, i was using a sip and it needs a lot more than that
is the plain water rule actually load bearing or is it a formality
coffee doesnt count
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i use it because needles are a genuine problem for me, not because i think its better
why is the oral dose in mg so much bigger than the injectable one
i said 17 months ago that my oral results were random, they got consistent once i fixed the water
mine was patchy too
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anyone dosing oral because of a needle problem rather than preference
*Medutest not the other one