vialroom
Thread · #maintenance · 2026-04-26

why fortnightly dosing is pharmacologically odd but not absurd

Spun off from a message in #maintenance on 2026-04-26. 6 messages, 2 participants.

The message this came from
  • tarpit_tam — the reason it isnt absurd is the half-life. about a week means a fortnightly schedule still leaves you with meaningful drug on board at day 14 16:40
TT

the reason it is odd is that you deliberately build a peak and a trough where weekly dosing was designed to flatten both

so you would expect appetite to come and go on a two week rhythm. which is exactly what people report

MG

thats me. days 1-8 quiet, days 9-14 the noise comes back and i eat like the old me on day 13

TT

and if your day 13 undoes your days 1-8 then youve invented a fortnightly diet cycle, not a maintenance dose

TT

none of that is data. its a curve and a guess. treat it as a curve and a guess