the people who do best here are almost always the ones going slowest
#dosing-titration 2026-06-08
Monday24 messages8 participantstimes are UTC
Highlights from this day
i escalate on symptoms. if the current dose is still doing something i stay on it, ymmv
nobody here can tell you what dose to be on and the ones who try get corrected
On this day 3 years ago this channel logged 27 messages.
steady state is 5 weeks
hold
two weeks is nothing
whats the longest anyone has stayed on one dose
how do you decide between holding and stepping when both feel wrong
do you count from injection day or from when you actually felt it
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go slower
came down from a treatment dose to maintenance over about three months and it was uneventful
U-100 syringe: 1 unit = 0.01 ml
10u = 0.10 ml
25u = 0.25 ml
50u = 0.50 ml
100u = 1.00 ml
mg drawn = ml drawn x mg/mlafter a gap of more than about three weeks i restart one rung lower. thats my own rule, not advice
thats anecdote
how much does the last dose still matter 4 days later
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came down, no regrets
is there any actual reason to escalate every 4 weeks other than the trial did it
if the current dose is still working, going up is spending headroom you might want later, thats just me
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pick a day and stick to it
do you escalate on the calendar or on how you feel
if i hold at 7.5 indefinitely am i losing anything
is week 31 too early to be thinking about the next step
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holding is not failing. most people here who lasted two years held at least one dose for months
split dosing has no trial behind it. people here do it and report on it, thats all