with a roughly seven day half-life you are near steady state after about five weeks at a dose
i escalate on symptoms. if the current dose is still doing something i stay on it
#dosing-titration 2025-11-12
Wednesday14 messages5 participantstimes are UTC
Highlights from this day
- month_six_me — with a roughly seven day half-life you are near steady state after about five weeks at a dose i escalate on symptoms. if the current dose is still doing something i… 18:19
- lead_time_lars — came down from a treatment dose to maintenance over about three months and it was uneventful 18:20
- month_six_me — the trials escalated on a fixed schedule because a trial has to. you are not a trial 19:31
- ten_of_ten — follow up split dosing has no trial behind it. people here do it and report on it, thats all 19:32
- chlorhex — stepping back down on purpose is a completely reasonable move and this channel should say so more often 19:59
came down from a treatment dose to maintenance over about three months and it was uneventful
i went from 12 to 0.5 and honestly could not tell the difference in appetite
is it normal for appetite to come back at the end of the week
coming back to this do you escalate on the calendar or on how you feel
how long did you hold at 7.5 before you moved up
held for months
too early imo
the trials escalated on a fixed schedule because a trial has to. you are not a trial
follow up split dosing has no trial behind it. people here do it and report on it, thats all
n of 1
steady state is 5 weeks
stepping back down on purpose is a completely reasonable move and this channel should say so more often