split dosing has no trial behind it. people here do it and report on it, thats all
#dosing-titration 2025-10-05
Sunday28 messages6 participantstimes are UTC
Highlights from this day
- sasha_stacks — the people who do best here are almost always the ones going slowest 18:06
- combo_cai — unrelated but a missed week does not reset you, but going straight back to the top dose after a gap is how people get floored 19:24
- tarpit_tam — the argument for splitting is a flatter curve. the argument against is you have doubled your injections for a guess 19:41
- tarpit_tam — my titration ladder took 17 months to climb and i would do it slower again 20:13
no trial for that
while im here i drifted from sunday to wednesday over a year and only noticed when i checked the log
whats the longest anyone has stayed on one dose
my rule: if a side effect is still there at day five, i hold. if it clears by day three, i step, thats just me
go slower
stepping back down on purpose is a completely reasonable move and this channel should say so more often
came down, no regrets
you do not have to escalate at all. that is a real option that gets forgotten
the trials escalated on a fixed schedule because a trial has to. you are not a trial
the people who do best here are almost always the ones going slowest
[edited]🤝5🎉5
too early imo
nobody here can tell you what dose to be on and the ones who try get corrected
held for months
how do you tell a plateau from just being at your set point
if it "stopped working after four days" that is almost never pharmacokinetics
plateau versus set point is not answerable in under six months of data, thats just me
quick one after a gap of more than about three weeks i restart one rung lower. thats my own rule, not advice
unrelated but a missed week does not reset you, but going straight back to the top dose after a gap is how people get floored
holding is not failing. most people here who lasted two years held at least one dose for months
is there a point where going up stops buying you anything
🔥1
the argument for splitting is a flatter curve. the argument against is you have doubled your injections for a guess
if the current dose is still working, going up is spending headroom you might want later
for the archive small steps are better than big ones and the only reason people take big ones is impatience
if you are going up because the scale stalled for two weeks, wait. two weeks is noise
anyone here split their weekly into two and would they do it again
my titration ladder took 17 months to climb and i would do it slower again