two weeks is nothing
#dosing-titration 2025-09-27
- mg_per_ml — right so whats the longest anyone has stayed on one dose 15:50
- mg_per_ml — right so a missed week does not reset you, but going straight back to the top dose after a gap is how people get floored 15:52
- mg_per_ml — if it "stopped working after four days" that is almost never pharmacokinetics 15:53
- constipation_con — i went to the top of the ladder, felt no better than two rungs down, and came back. that is data for me and nobody else, take that with a pinch of salt 15:57
i went up too fast and im paying for it, do i drop back or ride it out
i went from 2.5 to 15 and honestly could not tell the difference in appetite
the people who do best here are almost always the ones going slowest
with a roughly seven day half-life you are near steady state after about five weeks at a dose
coming back to this dose day drift is mostly harmless with a weekly compound, but pick a day and defend it
if you are going up because the scale stalled for two weeks, wait. two weeks is noise
nobody here can tell you what dose to be on and the ones who try get corrected
my dose day has drifted 5 days later over 19 months, does it matter
i log dose, day, weight and one line about how the week felt. thats enough to make decisions on, someone check my working
if the current dose is still working, going up is spending headroom you might want later
right so whats the longest anyone has stayed on one dose
right so a missed week does not reset you, but going straight back to the top dose after a gap is how people get floored
if it "stopped working after four days" that is almost never pharmacokinetics
thats anecdote
how much does the last dose still matter 3 days later
i went to the top of the ladder, felt no better than two rungs down, and came back. that is data for me and nobody else, take that with a pinch of salt
came down from a treatment dose to maintenance over about three months and it was uneventful