for the archive is week 12 too early to be thinking about the next step
#dosing-titration 2025-06-01
Sunday36 messages9 participantstimes are UTC
Highlights from this day
- subq_sy — came down from a treatment dose to maintenance over about three months and it was uneventful 18:31
- typosquat_tay — right so holding is not failing. most people here who lasted two years held at least one dose for months 18:53
- pbs_pip — i log dose, day, weight and one line about how the week felt. thats enough to make decisions on 19:52
- VialBot — New independent result logged — GGPeps, lot F-1330, purity 99.4% (VendorInvestigate). 19:53
- tarpit_tam — i jumped a rung once to catch up after a supply gap and it was a bad week. would not repeat 21:04
half life is a week
while im here appetite returning at the end of the week is extremely common and is not the dose failing
plateau versus set point is not answerable in under six months of data
came down from a treatment dose to maintenance over about three months and it was uneventful
unrelated but the people who do best here are almost always the ones going slowest
slightly off topic but the honest answer is that most of us are running protocols nobody has ever studied
follow up whats your rule for when a side effect means hold rather than push
right so holding is not failing. most people here who lasted two years held at least one dose for months
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is there a point where going up stops buying you anything
if you are asking whether to go up, the fact you are asking usually means not yet
came down, no regrets
[edited]no trial for that
peptidemeter-summary-h-2814.pdf
2 pages · 217 KB · not retained in the public archive
anyone here split their weekly into two and would they do it again
follow up i went to the top of the ladder, felt no better than two rungs down, and came back. that is data for me and nobody else, still working it out
thats anecdote
the argument for splitting is a flatter curve. the argument against is you have doubled your injections for a guess
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i would hold
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held for months
i log dose, day, weight and one line about how the week felt. thats enough to make decisions on
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New independent result logged — GGPeps, lot F-1330, purity 99.4% (VendorInvestigate).
thats normal
right so my rule: if a side effect is still there at day five, i hold. if it clears by day three, i step
nobody here can tell you what dose to be on and the ones who try get corrected
split dosing has no trial behind it. people here do it and report on it, thats all
if the current dose is still working, going up is spending headroom you might want later
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n of 1
too early imo
my titration ladder took 19 months to climb and i would do it slower again
go slower
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update from 1 months ago: held at the same dose the whole time and still losing slowly
i escalate on symptoms. if the current dose is still doing something i stay on it
i jumped a rung once to catch up after a supply gap and it was a bad week. would not repeat
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end of week thing
pick a day and stick to it
not advice
two weeks is nothing