genuine question if the current dose is still working, going up is spending headroom you might want later
#dosing-titration 2025-05-28
Wednesday24 messages7 participantstimes are UTC
Highlights from this day
- turnaround_tam — genuine question if the current dose is still working, going up is spending headroom you might want later 21:13
- turnaround_tam — if you are going up because the scale stalled for two weeks, wait. two weeks is noise 21:21
- VialBot — Verification log updated: BCH — evidence added, status unchanged. 21:34
- septum_sal — i jumped a rung once to catch up after a supply gap and it was a bad week. would not repeat 22:03
- two_four_ceiling — my rule: if a side effect is still there at day five, i hold. if it clears by day three, i step 23:16
update question: did anyone who held for 16 months regret it
if you are going up because the scale stalled for two weeks, wait. two weeks is noise
📉18😂1
half life is a week
thats anecdote
📈4🧊6🧪7
came down from a treatment dose to maintenance over about three months and it was uneventful
Verification log updated: BCH — evidence added, status unchanged.
🙏5
appetite returning at the end of the week is extremely common and is not the dose failing
thats noise
the trials escalated on a fixed schedule because a trial has to. you are not a trial
steady state is 5 weeks
*week 32 not week 7
i jumped a rung once to catch up after a supply gap and it was a bad week. would not repeat
my titration ladder took 16 months to climb and i would do it slower again
does a missed week reset anything or do you just carry on
n of 1
whats a sensible maintenance dose after a year at treatment dose
came down, no regrets
is there a trial anywhere that studied twice weekly, or is it all anecdote
ok so coming down from 2.5 to 2.4, how bad is the appetite rebound
my rule: if a side effect is still there at day five, i hold. if it clears by day three, i step
🧪8😂5
end of week thing
not advice