#dosing-titration 2025-03-18

Tuesday22 messages7 participantstimes are UTC

Highlights from this day

gall_bladder_gav — nobody here can tell you what dose to be on and the ones who try get corrected, for what its worth 14:20
stack_sceptic — my titration ladder took 13 months to climb and i would do it slower again 14:29
quiet.hours — i went to the top of the ladder, felt no better than two rungs down, and came back. that is data for me and nobody else 14:56
relabel_watch — if it "stopped working after four days" that is almost never pharmacokinetics 17:34

the honest answer is that most of us are running protocols nobody has ever studied

if i took it 2 days late do i shift the schedule or go back to the old day

steady state is 5 weeks

half life is a week

thats normal

nobody here can tell you what dose to be on and the ones who try get corrected, for what its worth

does a missed week reset anything or do you just carry on

do you tell your prescriber you held or do you just hold

my titration ladder took 13 months to climb and i would do it slower again

U-100 syringe: 1 unit = 0.01 ml
  10u = 0.10 ml
  25u = 0.25 ml
  50u = 0.50 ml
 100u = 1.00 ml
mg drawn = ml drawn x mg/ml

i hold for two months minimum before i decide a dose has stopped doing anything

i went to the top of the ladder, felt no better than two rungs down, and came back. that is data for me and nobody else

i have been at 0.5 for 15 months and honestly i have stopped wanting to move

how long did you hold at 2.4 before you moved up

do you count from injection day or from when you actually felt it

i jumped a rung once to catch up after a supply gap and it was a bad week. would not repeat

anyone here split their weekly into two and would they do it again

go slower

the ladder in the trials is a starting point, not a schedule you owe anyone

you do not have to escalate at all. that is a real option that gets forgotten

held for months

if it "stopped working after four days" that is almost never pharmacokinetics

🔥13👀2😂4

i drifted from sunday to wednesday over a year and only noticed when i checked the log