i drifted from sunday to wednesday over a year and only noticed when i checked the log
| Trial schedule | What most people here do | |
|---|---|---|
| Step interval | 4 weeks, fixed | 4-12 weeks, on symptoms |
| Holding | protocol deviation | normal and expected |
| Top dose | reached by design | often never reached |
| Coming down | not studied | common at maintenance |
i hold for two months minimum before i decide a dose has stopped doing anything
split dosing has no trial behind it. people here do it and report on it, thats all
i went up too fast and im paying for it, do i drop back or ride it out
how do you tell a plateau from just being at your set point
i jumped a rung once to catch up after a supply gap and it was a bad week. would not repeat
the people who do best here are almost always the ones going slowest, thats just me
small steps are better than big ones and the only reason people take big ones is impatience
holding is not failing. most people here who lasted two years held at least one dose for months
do you escalate on the calendar or on how you feel
whats the longest anyone has stayed on one dose
[edited]how long did you hold at 2 before you moved up
| Trial schedule | What most people here do | |
|---|---|---|
| Step interval | 4 weeks, fixed | 4-12 weeks, on symptoms |
| Holding | protocol deviation | normal and expected |
| Top dose | reached by design | often never reached |
| Coming down | not studied | common at maintenance |
nobody here can tell you what dose to be on and the ones who try get corrected
stepping back down on purpose is a completely reasonable move and this channel should say so more often, n of 1 obviously
is there any actual reason to escalate every 4 weeks other than the trial did it
does a missed week reset anything or do you just carry on
if it "stopped working after four days" that is almost never pharmacokinetics
anyone tracked whether a smaller more frequent dose changed their side effects
i have been at 1.7 for 16 months and honestly i have stopped wanting to move
coming down from 1.7 to 0.25, how bad is the appetite rebound
i went from 5 to 0.5 and honestly could not tell the difference in appetite
if i hold at 0.5 indefinitely am i losing anything
i log dose, day, weight and one line about how the week felt. thats enough to make decisions on
is there a trial anywhere that studied twice weekly, or is it all anecdote
[edited]not advice
came down, no regrets
end of week thing
how much does the last dose still matter 9 days later
follow up you do not have to escalate at all. that is a real option that gets forgotten
the ladder in the trials is a starting point, not a schedule you owe anyone
if you are going up because the scale stalled for two weeks, wait. two weeks is noise
plateau versus set point is not answerable in under six months of data
appetite returning at the end of the week is extremely common and is not the dose failing