#dosing-titration 2024-10-08

Tuesday18 messages5 participantstimes are UTC

Highlights from this day

quiet_head_qi — a missed week does not reset you, but going straight back to the top dose after a gap is how people get floored 17:20
quiet_head_qi — dose day drift is mostly harmless with a weekly compound, but pick a day and defend it 17:52
madrid_mg — split dosing has no trial behind it. people here do it and report on it, thats all, happy to be corrected 18:36
pin29g — update from 20 months ago: held at the same dose the whole time and still losing slowly 18:45
quiet_head_qi — nobody here can tell you what dose to be on and the ones who try get corrected 19:00

hold

thats anecdote

wk 1-4    0.25mg
wk 5-10   0.50mg   (held 2 extra weeks)
wk 11-14  1.00mg
wk 15-26  1.70mg   (held, long)
wk 27+    2.40mg

🤝1

thats normal

✅14😂6

held for months

i have been at 5 for 20 months and honestly i have stopped wanting to move

a missed week does not reset you, but going straight back to the top dose after a gap is how people get floored

dose day drift is mostly harmless with a weekly compound, but pick a day and defend it

the ladder in the trials is a starting point, not a schedule you owe anyone

two weeks is nothing

end of week thing

split dosing has no trial behind it. people here do it and report on it, thats all, happy to be corrected

right so is week 5 too early to be thinking about the next step

whats your rule for when a side effect means hold rather than push

n of 1

💀11🎉4

how do you decide between holding and stepping when both feel wrong

update from 20 months ago: held at the same dose the whole time and still losing slowly

i went from 0.5 to 1 and honestly could not tell the difference in appetite

nobody here can tell you what dose to be on and the ones who try get corrected

wk 1-4    2.5mg
wk 5-8    5.0mg
wk 9-20   7.5mg   <- stayed here
wk 21-24  10.0mg  (no extra benefit for me)
wk 25+    7.5mg   (came back down)