steady state is 5 weeks
#dosing-titration 2024-09-11
Wednesday27 messages4 participantstimes are UTC
Highlights from this day
- igf_one_ivy — if the current dose is still working, going up is spending headroom you might want later 18:41
- u100_pat — whats your rule for when a side effect means hold rather than push i jumped a rung once to catch up after a supply gap and it was a bad week. would not repeat 19:10
- VialBot — On this day 3 years ago this channel logged 33 messages. 19:15
- u100_pat — i hold for two months minimum before i decide a dose has stopped doing anything 21:06
- u100_pat — stepping back down on purpose is a completely reasonable move and this channel should say so more often, ill dig out the number 21:10
if the current dose is still working, going up is spending headroom you might want later
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if you are going up because the scale stalled for two weeks, wait. two weeks is noise
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is week 11 too early to be thinking about the next step
i would hold
[edited]small steps are better than big ones and the only reason people take big ones is impatience, ask me again in a month
while im here is there a trial anywhere that studied twice weekly, or is it all anecdote
whats your rule for when a side effect means hold rather than push
i jumped a rung once to catch up after a supply gap and it was a bad week. would not repeat
follow up split dosing has no trial behind it. people here do it and report on it, thats all
after a gap of more than about three weeks i restart one rung lower. thats my own rule, not advice
On this day 3 years ago this channel logged 33 messages.
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the people who do best here are almost always the ones going slowest
whats the longest anyone has stayed on one dose
i went from 2.4 to 5 and honestly could not tell the difference in appetite
half life is a week
how do you tell a plateau from just being at your set point
update question: did anyone who held for 24 months regret it
came down, no regrets
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quick one came down from a treatment dose to maintenance over about three months and it was uneventful, thats just me
update from 17 months ago: held at the same dose the whole time and still losing slowly, we shall see
appetite returning at the end of the week is extremely common and is not the dose failing
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held for months
i hold for two months minimum before i decide a dose has stopped doing anything
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end of week thing
stepping back down on purpose is a completely reasonable move and this channel should say so more often, ill dig out the number
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i escalate on symptoms. if the current dose is still doing something i stay on it