#dosing-titration 2024-06-20

half life is a week

i drifted from sunday to wednesday over a year and only noticed when i checked the log

if i hold at 1.7 indefinitely am i losing anything
if you are asking whether to go up, the fact you are asking usually means not yet

how do you tell a plateau from just being at your set point

hold

is week 5 too early to be thinking about the next step

if you are asking whether to go up, the fact you are asking usually means not yet

quick one split dosing has no trial behind it. people here do it and report on it, thats all

a missed week does not reset you, but going straight back to the top dose after a gap is how people get floored

you do not have to escalate at all. that is a real option that gets forgotten
the honest answer is that most of us are running protocols nobody has ever studied

whats a sensible maintenance dose after a year at treatment dose

go slower

the trials escalated on a fixed schedule because a trial has to. you are not a trial

appetite returning at the end of the week is extremely common and is not the dose failing

i went to the top of the ladder, felt no better than two rungs down, and came back. that is data for me and nobody else, not advice obviously
if it "stopped working after four days" that is almost never pharmacokinetics

how much does the last dose still matter 8 days later

holding is not failing. most people here who lasted two years held at least one dose for months, n of 1 obviously

i have been at 0.25 for 10 months and honestly i have stopped wanting to move

i escalate on symptoms. if the current dose is still doing something i stay on it

two weeks is nothing

what does the room think about jumping a rung to catch up

thats noise