came down, no regrets
| Trial schedule | What most people here do | |
|---|---|---|
| Step interval | 4 weeks, fixed | 4-12 weeks, on symptoms |
| Holding | protocol deviation | normal and expected |
| Top dose | reached by design | often never reached |
| Coming down | not studied | common at maintenance |
if you are asking whether to go up, the fact you are asking usually means not yet
you do not have to escalate at all. that is a real option that gets forgotten
whats the smallest step anyone has managed between doses
my rule: if a side effect is still there at day five, i hold. if it clears by day three, i step
is week 21 too early to be thinking about the next step
wk 1-4 0.25mg
wk 5-10 0.50mg (held 2 extra weeks)
wk 11-14 1.00mg
wk 15-26 1.70mg (held, long)
wk 27+ 2.40mgcoming back to this appetite returning at the end of the week is extremely common and is not the dose failing
genuine question update from 15 months ago: held at the same dose the whole time and still losing slowly
whats your rule for when a side effect means hold rather than push
split dosing has no trial behind it. people here do it and report on it, thats all
thats anecdote