#dosing-titration 2024-01-07

n of 1

half life is a week

whats a sensible maintenance dose after a year at treatment dose

held for months

the ladder in the trials is a starting point, not a schedule you owe anyone

whats your rule for when a side effect means hold rather than push

slightly off topic but i went to the top of the ladder, felt no better than two rungs down, and came back. that is data for me and nobody else

after a gap of more than about three weeks i restart one rung lower. thats my own rule, not advice

i would hold

go slower

i log dose, day, weight and one line about how the week felt. thats enough to make decisions on

the honest answer is that most of us are running protocols nobody has ever studied

two weeks is nothing

if the current dose is still working, going up is spending headroom you might want later

holding is not failing. most people here who lasted two years held at least one dose for months

appetite returning at the end of the week is extremely common and is not the dose failing, for what its worth