water content is why an honest 10mg vial assays at 9.1. karl fischer titration, and most certificates omit it, n of 1 obviously
#coa-reading 2025-09-22
- hiccup_hollis — i keep every certificate in a dated folder and compare them. two suppliers had not changed their template since 2019 19:32
- assay_not_purity — a vial can be 99.4% pure and hold 8.1mg of a 10mg label. both numbers are true and only one of them is the one you care about 19:38
- VialBot — Reminder for apnoea_down_two: dose day is today. Set 6 days ago. 20:38
i keep every certificate in a dated folder and compare them. two suppliers had not changed their template since 2019
purity is what fraction of the contents is the target. assay is how many mg are actually there. different questions
a vial can be 99.4% pure and hold 8.1mg of a 10mg label. both numbers are true and only one of them is the one you care about
i have never seen a research certificate with an endotoxin result on it. not once
does purity by hplc at one wavelength miss things
for the archive my 15mg vial weighed more than 2mg of powder, is the certificate lying
the font on this one changes halfway down, am i being paranoid
not detected means nothing
ask for water content
residual solvents matter more than people think for anything that went through a lot of purification steps
thats the counterion
is endotoxin ever tested on research material
same chromatogram
Reminder for apnoea_down_two: dose day is today. Set 6 days ago.
an identical chromatogram on two different lots is the single biggest tell there is
is sterility tested as part of a normal purity certificate
the retention time on this one is different from the last lot, problem
looks re-dated
a lab that reports "greater than 98%" rather than a number is telling you they did not integrate carefully
residual solvents matter more than people think for anything that went through a lot of purification steps