#cagrilintide 2026-06-24

fullness rather than nausea

quick one 30 in 2.5ml gives 5mg/ml which is what i use, purely because the units come out round

the nausea felt different rather than less, more fullness and less of the queasy wave

slower than the others

held at 10 for 2 months on monotherapy before i touched it again, ymmv

underwhelming honestly

weekly for me, same day every week, no reason beyond habit

did the combination change your GI compared to the GLP-1 alone

the numbers everyone quotes come from the combination, so comparing them to monotherapy logs is unfair
nobody should copy my schedule, im describing it because people asked what a slow ramp looks like

dosing them on different days made no difference i could detect
weekly for me, same day every week, no reason beyond habit

cagrisema thats it

the slower titration in here is community habit as much as anything, the trials had their own schedule

REDEFINE is the phase 3 programme, most of what gets quoted casually in here is earlier work

lost 16lb over 8 months on the combination and i genuinely cannot apportion it

unrelated but the fullness thing is the part people describe differently, food stops being interesting rather than repellent

is the nausea profile genuinely different or am i imagining it

added it to an existing cagrilintide dose rather than starting both, which made attribution possible

two Janoshik results on the same SGN lot came back 98.1 and 97.4, closer than i expected