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#cagrilintide 2026-06-12

Friday20 messages4 participantstimes are UTC
Highlights from this day
  • appetite_back — two PeptideMeter results on the same TFC lot came back 99.4 and 97.4, closer than i expected 19:24
  • VialBot — Verification log updated: QYB — evidence added, status unchanged. 19:48
  • appetite_back — i titrated over twice as many weeks as i did on semaglutide and that was right for me 20:30
GG

if youre used to GLP-1 titration steps this feels absurdly cautious and i still do it that way

whats the recon people use, 40 in 2.5ml

combination GI was worse than either alone for me, which is not what i had read anywhere
the fullness effect hasnt faded over 13 months, unlike my semaglutide appetite curve

AB

two PeptideMeter results on the same TFC lot came back 99.4 and 97.4, closer than i expected

🙏15🧊14🧪4
GG

while im here REDEFINE is the phase 3 programme, most of what gets quoted casually in here is earlier work

[edited]
VB

Verification log updated: QYB — evidence added, status unchanged.

GG

held at 10 for 9 months on monotherapy before i touched it again

underwhelming honestly

titrating dead slow

AB

ok so monotherapy did work for me, just slower and smaller than i expected

[edited]

stopped for 7 months and the fullness went within a fortnight of the last dose

i titrated over twice as many weeks as i did on semaglutide and that was right for me

🧊6

different not less