£38 for a 20 vial and it lasts me longer than the GLP-1 does at my doses
#cagrilintide 2026-02-11
Wednesday37 messages8 participantstimes are UTC
Highlights from this day
- dark_for_ten_days — £38 for a 20 vial and it lasts me longer than the GLP-1 does at my doses 17:52
- juno_joins — two VendorInvestigate results on the same KP lot came back 97.4 and 99, closer than i expected 18:00
- juno_joins — went slower because the first step gave me two rough days and i took that as information the slower titration in here is community habit as much as anything, the… 18:49
- abdo_two_inch — update on the earlier thing anyone stopped the GLP-1 and kept only this 19:09
- abdo_two_inch — whats the recon people use, 15 in 3ml 19:10
i titrated over twice as many weeks as i did on semaglutide and that was right for me
is the combination just the two dosed together or a single formulation
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slower than the others
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two VendorInvestigate results on the same KP lot came back 97.4 and 99, closer than i expected
changed my mind on this, i started thinking amylin was the interesting bit and now i think its the pairing
the slower titration in here is community habit as much as anything, the trials had their own schedule
if youre used to GLP-1 titration steps this feels absurdly cautious and i still do it that way
ok so back after 26 months, is monotherapy still a minority thing here
REDEFINE is the trial
different not less
noticed something around week 33 on monotherapy, well after i had given up expecting to
went slower because the first step gave me two rough days and i took that as information
the slower titration in here is community habit as much as anything, the trials had their own schedule
the nausea felt different rather than less, more fullness and less of the queasy wave, someone check my working
follow up how slow are people titrating this compared to semaglutide
held at 2.4 for 7 months on monotherapy before i touched it again
monotherapy did work for me, just slower and smaller than i expected
update on the earlier thing anyone stopped the GLP-1 and kept only this
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whats the recon people use, 15 in 3ml
stopped for 3 months and the fullness went within a fortnight of the last dose
dropped the GLP-1 and stayed on this alone for 7 months, appetite held but weight barely moved
monotherapy here
the combination is the thing with trial data behind it, monotherapy in here is mostly us guessing
anyone dosing this on a different day to their tirzepatide
nobody should copy my schedule, im describing it because people asked what a slow ramp looks like, someone check my working
REDEFINE is the phase 3 programme, most of what gets quoted casually in here is earlier work
is 2.4 the number for this too or am i confusing compounds
[edited]thats the phase 3 one
weekly for me, same day every week, no reason beyond habit
did the nausea feel different to you or just less
added it to an existing retatrutide dose rather than starting both, which made attribution possible
combination GI was worse than either alone for me, which is not what i had read anywhere
its an amylin analogue, different receptor family, so treating it as another GLP-1 is the first mistake, someone check my working
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did anyone find monotherapy underwhelming
underwhelming honestly
does the fullness effect fade the way appetite suppression does