5 in 0.5ml gives 10mg/ml which is what i use, purely because the units come out round
#cagrilintide 2025-10-23
Thursday15 messages5 participantstimes are UTC
Highlights from this day
- first_month_fi — while im here does amylin do something about fullness that the GLP-1 doesnt 20:05
- ghent_gradient — the slower titration in here is community habit as much as anything, the trials had their own schedule 20:37
- nordic_price_nils — i said earlier this year that monotherapy did nothing for me, and at a higher dose it did something 20:51
while im here does amylin do something about fullness that the GLP-1 doesnt
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combination GI was worse than either alone for me, which is not what i had read anywhere
is anyone running this on its own or is it all CagriSema in here
[edited]REDEFINE is the phase 3 programme, most of what gets quoted casually in here is earlier work
cagrisema thats it
the fullness thing is the part people describe differently, food stops being interesting rather than repellent, n of 1 obviously
the fullness effect hasnt faded over 23 months, unlike my semaglutide appetite curve
[edited]has REDEFINE reported or are people quoting earlier work
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stopped for 13 months and the fullness went within a fortnight of the last dose
the slower titration in here is community habit as much as anything, the trials had their own schedule
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noticed something around week 6 on monotherapy, well after i had given up expecting to
amylin is about slowed gastric emptying and satiety signalling, thats the short version and im no pharmacologist
i said earlier this year that monotherapy did nothing for me, and at a higher dose it did something
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slightly off topic but dropped the GLP-1 and stayed on this alone for 22 months, appetite held but weight barely moved