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Thread · #tirzepatide · 2026-01-17

does the appetite effect feel different or just stronger

Spun off from a message in #tirzepatide on 2026-01-17. 16 messages, 4 participants.

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tga_notice — does the appetite effect feel different or just stronger 18:51

checked the units twice

gradient_greg 18:58

is SURMOUNT-OSA the sleep apnoea one

🔥3👀1

tga_notice 19:01

anyone stopped at 10 and stayed there for months

7.5 gang

step_one_sian 19:12

the trials titrated every four weeks to a target, most people here stop at whatever works

ruo_only checked the units twice

tga_notice 19:15

SURMOUNT-OSA was the sleep apnoea trial and it is not a weight headline however its quoted

❤️6🧪2

the GI difference held for me right up to 15, which isnt what a couple of people here found

gradient_greg 19:18

is 7.5 really the sweet spot or is that just channel folklore

im at 0.25 and thinking about 5, did anyone gain anything from that step

gradient_greg 19:33

switched last year

gradient_greg is 7.5 really the sweet spot or is that just channel folklore

gradient_greg 19:40

start low anyway

how did people handle the 2.5 to 5 jump

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tga_notice 19:54

i sat at 7.5 for 9 months and never needed more, which is where the folklore comes from

step_one_sian 20:02

same plateau here

GIP plus GLP-1

tga_notice 20:12

the 2.5 to 5 step was the roughest one for me and everything after was easier

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