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Thread · #tirzepatide · 2025-11-02

update on the earlier thing same plateau here

Spun off from a message in #tirzepatide on 2025-11-02. 12 messages, 3 participants.

The message this came from
  • third_shift — update on the earlier thing same plateau here 18:15
OW

12 did nothing extra over 10 for me and that still holds a year later

SD

the trials titrated every four weeks to a target, most people here stop at whatever works

titrate slow

there is no clean conversion between the two, anyone giving you a ratio is guessing

SURMOUNT-1 versus SURPASS-2, which one was the weight trial

📈6❤️2

the two compounds arent interchangeable week for week even if the effect ends up similar

restarted at 2.5 after 3 months off and the first two doses reminded me why titration exists

TS

held 10 for 7 months and lost 35kg over that stretch, slow and boring and fine

TS

dual agonist, GIP as well as GLP-1, thats the whole difference in one line

💀8