12 did nothing extra over 10 for me and that still holds a year later
update on the earlier thing same plateau here
Spun off from a message in #tirzepatide on 2025-11-02. 12 messages, 3 participants.
- third_shift — update on the earlier thing same plateau here 18:15
the trials titrated every four weeks to a target, most people here stop at whatever works
titrate slow
there is no clean conversion between the two, anyone giving you a ratio is guessing
SURMOUNT-1 versus SURPASS-2, which one was the weight trial
the two compounds arent interchangeable week for week even if the effect ends up similar
restarted at 2.5 after 3 months off and the first two doses reminded me why titration exists
held 10 for 7 months and lost 35kg over that stretch, slow and boring and fine
SURMOUNT-1 versus SURPASS-2, which one was the weight trial
dual agonist, GIP as well as GLP-1, thats the whole difference in one line
why does everyone talk about 7.5 and not 10
titrate slow