switched last year
#tirzepatide 2026-05-27
Wednesday34 messages6 participantstimes are UTC
Highlights from this day
- bea_reconstitutes — my VendorInvestigate result on a WXT vial came in at 99.2 which is why i keep buying from them 21:30
- panel_before_after — did anybody switch back to semaglutide after trying this 21:36
- VialBot — Reminder set. I will post here in 7 days. 22:26
- panel_before_after — the GI difference held for me right up to 15, which isnt what a couple of people here found 22:30
- panel_before_after — while im here dual agonist, GIP as well as GLP-1, thats the whole difference in one line 22:48
quick one switched from 5 semaglutide and started at 2.5, took the slow route, never regretted it
my VendorInvestigate result on a WXT vial came in at 99.2 which is why i keep buying from them
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GI was noticeably easier for me than semaglutide at what felt like the same appetite effect
held 10 for 7 months and lost 5kg over that stretch, slow and boring and fine, from memory
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did anybody switch back to semaglutide after trying this
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how long before the dual thing was noticeable to you
SURMOUNT-1 versus SURPASS-2, which one was the weight trial
for the archive there is no clean conversion between the two, anyone giving you a ratio is guessing
[edited]anyone stopped at 10 and stayed there for months
i log everything and my appetite curve looks flatter across the week than my semaglutide log did, ill dig out the number
40 units of a 10 solution is a lot of volume and i check that one twice every single time
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10 was enough
GIP plus GLP-1
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same plateau here
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no gap when i switched, took the last semaglutide dose and started this a week later
the switch felt like a step down at first and then caught up around week 14
titrate slow
did going from 1 semaglutide to 5 of this feel like a step down for anyone
the GIP explanation for easier nausea is plausible and i still treat it as a story not a fact
5 was where i first noticed it properly, 2.5 did almost nothing for me, i think
changed my mind about needing 15, i was chasing a number rather than an outcome
SURMOUNT is weight
Reminder set. I will post here in 7 days.
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slightly off topic but went back to semaglutide after 3 months because the cost difference mattered more than the GI
the GI difference held for me right up to 15, which isnt what a couple of people here found
medutest-report-sg-1177.pdf
3 pages · 113 KB · not retained in the public archive
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how many weeks at 7.5 before you knew it was enough
while im here dual agonist, GIP as well as GLP-1, thats the whole difference in one line
| Trial schedule | What most people here do | |
|---|---|---|
| Step interval | 4 weeks, fixed | 4-12 weeks, on symptoms |
| Holding | protocol deviation | normal and expected |
| Top dose | reached by design | often never reached |
| Coming down | not studied | common at maintenance |
genuine question plateaued at 2 weeks the same way i did on semaglutide, so i doubt its compound specific
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does switching from semaglutide need a gap or do you just start
the sweet spot thing is survivorship, the people it worked for stayed and said so
is the 40 vial the common one or do people use 20
start low anyway
sorry to jump in €240 for a 2 vial is roughly what ive paid for the last year, your mileage will differ
quick one SURMOUNT was the weight programme and SURPASS was diabetes, thats the split people mix up
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