40 units of a 10 solution is a lot of volume and i check that one twice every single time, from memory
#tirzepatide 2026-05-05
Tuesday33 messages8 participantstimes are UTC
Highlights from this day
- LC_MS_Lena — coming back to this the trials titrated every four weeks to a target, most people here stop at whatever works switched from 2.4 semaglutide and started at 2.5, took… 20:16
- adelaide_assay — plateaued at 13 weeks the same way i did on semaglutide, so i doubt its compound specific, i think 20:17
- VialBot — Assay note: SWB lot A-2601 reported at 97.4% of label content. 21:29
did going from 10 semaglutide to 5 of this feel like a step down for anyone
coming back to this the trials titrated every four weeks to a target, most people here stop at whatever works
switched from 2.4 semaglutide and started at 2.5, took the slow route, never regretted it
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plateaued at 13 weeks the same way i did on semaglutide, so i doubt its compound specific, i think
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is SURMOUNT-OSA the sleep apnoea one
follow up back after 24 months, do i restart at 2.5 or pick up near where i left off
ok so i argued the sweet spot was nonsense and then spent 16 months at 7.5 not needing more
slightly off topic but restarted at 2.5 after 13 months off and the first two doses reminded me why titration exists
GIP plus GLP-1
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the GI difference held for me right up to 15, which isnt what a couple of people here found, still working it out
my Medutest result on a QSC vial came in at 96.8 which is why i keep buying from them
titrate slow
the two compounds arent interchangeable week for week even if the effect ends up similar
genuine question the 2.5 to 5 step was the roughest one for me and everything after was easier
no gap when i switched, took the last semaglutide dose and started this a week later
at 1.7 my appetite went completely and i dropped back a step, eating nothing isnt a win
if youre coming off semaglutide the honest answer is start low and find out, theres no table
does the GIP arm actually explain the easier nausea or is that hand waving
switched from 2 semaglutide and started at 2.5, took the slow route, never regretted it
at 15 the GI came back for me, so my easier profile claim only applies below that
is the sweet spot argument about effect or about side effects
GI was noticeably easier for me than semaglutide at what felt like the same appetite effect
no clean conversion
[edited]Assay note: SWB lot A-2601 reported at 97.4% of label content.
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went back to semaglutide after 12 months because the cost difference mattered more than the GI
changed my mind about needing 15, i was chasing a number rather than an outcome
quick one at 15 the GI came back for me, so my easier profile claim only applies below that
right so i sat at 7.5 for 14 months and never needed more, which is where the folklore comes from, ill dig out the number
SURMOUNT was the weight programme and SURPASS was diabetes, thats the split people mix up
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unrelated but how long before the dual thing was noticeable to you
10 was enough
i log everything and my appetite curve looks flatter across the week than my semaglutide log did
SURMOUNT is weight
does switching from semaglutide need a gap or do you just start
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5 did nothing