#tirzepatide 2026-05-01

Friday16 messages5 participantstimes are UTC

Highlights from this day

satiety_sig — the sweet spot thing is survivorship, the people it worked for stayed and said so 18:27
lead_time_lars — whats the plateau pattern here, same as semaglutide or different 18:29
lead_time_lars — the two compounds arent interchangeable week for week even if the effect ends up similar 18:54
bpc_sceptic — GI was noticeably easier for me than semaglutide at what felt like the same appetite effect 20:21

i sat at 7.5 for 17 months and never needed more, which is where the folklore comes from

the sweet spot thing is survivorship, the people it worked for stayed and said so

✅1😂9🎉1

whats the plateau pattern here, same as semaglutide or different

😂1⚠️14

the two compounds arent interchangeable week for week even if the effect ends up similar

wk 1-4    2.5mg
wk 5-8    5.0mg
wk 9-20   7.5mg   <- stayed here
wk 21-24  10.0mg  (no extra benefit for me)
wk 25+    7.5mg   (came back down)

coming back to this is the 2 vial the common one or do people use 30

no clean conversion

🔥10

the trials titrated every four weeks to a target, most people here stop at whatever works

unrelated but does the GIP arm actually explain the easier nausea or is that hand waving

did anybody switch back to semaglutide after trying this

the 15 vial in 0.5ml gives 10mg/ml which puts 2 on 25 units, nice round numbers

switched last year

💀11📉1👀1

is there a reason to titrate slower than the four week schedule

switched from 0.5 semaglutide and started at 2.5, took the slow route, never regretted it

at 2 my appetite went completely and i dropped back a step, eating nothing isnt a win

GI was noticeably easier for me than semaglutide at what felt like the same appetite effect

7.5 gang