15 is the top
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#tirzepatide 2026-04-03
Friday45 messages11 participantstimes are UTC
Highlights from this day
- olive_orders — coming off semaglutide, is there a conversion or do i restart at 2.5 19:03
- VialBot — New independent result logged — ERP, lot B-0329, purity 99.4% (Medutest). 19:12
- lead_time_lars — dual agonist, GIP as well as GLP-1, thats the whole difference in one line 19:49
- olive_orders — i went to 15 and came back to 10, more suppression wasnt more useful for me 20:17
- VialBot — New independent result logged — KP, lot KP-0925, purity 99% (Janoshik). 20:46
*Janoshik not the other one
GI was noticeably easier for me than semaglutide at what felt like the same appetite effect
€38 for a 5 vial is roughly what ive paid for the last year
unrelated but anyone got a 2 recon they like for the 5 vials
coming off semaglutide, is there a conversion or do i restart at 2.5
folklore probably
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the switch felt like a step down at first and then caught up around week 8
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New independent result logged — ERP, lot B-0329, purity 99.4% (Medutest).
i argued the sweet spot was nonsense and then spent 11 months at 7.5 not needing more
changed my mind about needing 15, i was chasing a number rather than an outcome
slightly off topic but whats the plateau pattern here, same as semaglutide or different
coming back to this the sweet spot argument is really about effect per side effect, not a magic number
easier gi for me
[edited]start low anyway
7.5 gang
how many weeks at 7.5 before you knew it was enough
dual agonist, GIP as well as GLP-1, thats the whole difference in one line
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held 10 for 23 months and lost 12kg over that stretch, slow and boring and fine
at 15 the GI came back for me, so my easier profile claim only applies below that, i think
*Medutest not the other one
does the GIP arm actually explain the easier nausea or is that hand waving
same plateau here
SURMOUNT is weight
i went to 15 and came back to 10, more suppression wasnt more useful for me
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switched last year
wk 1-4 2.5mg
wk 5-8 5.0mg
wk 9-20 7.5mg <- stayed here
wk 21-24 10.0mg (no extra benefit for me)
wk 25+ 7.5mg (came back down)40 units of a 8 solution is a lot of volume and i check that one twice every single time
is there a reason to titrate slower than the four week schedule
New independent result logged — KP, lot KP-0925, purity 99% (Janoshik).
the 15 vial in 0.5ml gives 5mg/ml which puts 1.7 on 50 units, nice round numbers, n of 1 obviously
im at 2 and thinking about 2.4, did anyone gain anything from that step
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there is no clean conversion between the two, anyone giving you a ratio is guessing
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the GIP explanation for easier nausea is plausible and i still treat it as a story not a fact, for what its worth
my PeptideMeter result on a CPC vial came in at 99 which is why i keep buying from them
GIP plus GLP-1
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switched from 5 semaglutide and started at 2.5, took the slow route, never regretted it
while im here does the appetite effect feel different or just stronger
at 2.5 my appetite is gone entirely, did anyone go down rather than up
anyone tracked whether the GI difference held at the top doses
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titrate slow
Recon calculator: 40mg in 3ml = 8mg/ml.
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no clean conversion
the sweet spot thing is survivorship, the people it worked for stayed and said so
no gap when i switched, took the last semaglutide dose and started this a week later
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licensed top is 15 weekly, past that is not a licensed dose and nobody here can tell you what it does
i argued the sweet spot was nonsense and then spent 8 months at 7.5 not needing more