SURMOUNT-OSA was the sleep apnoea trial and it is not a weight headline however its quoted
#tirzepatide 2026-02-16
Monday37 messages7 participantstimes are UTC
Highlights from this day
- vialkeeper — quick one is the 40 vial the common one or do people use 15 19:00
- vialkeeper — quick one coming off semaglutide, is there a conversion or do i restart at 2.5 the switch felt like a step down at first and then caught up around week 22 19:10
- VialBot — Reminder set. I will post here in 4 days. 20:21
- warsaw_vial — coming back to this anyone got a 4 recon they like for the 10 vials 20:56
- reship_rita — licensed top is 15 weekly, past that is not a licensed dose and nobody here can tell you what it does 21:45
did anybody switch back to semaglutide after trying this
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40 units of a 10 solution is a lot of volume and i check that one twice every single time
genuine question the two compounds arent interchangeable week for week even if the effect ends up similar
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i log everything and my appetite curve looks flatter across the week than my semaglutide log did
plateaued at 17 weeks the same way i did on semaglutide, so i doubt its compound specific
same plateau here
checked the units twice
quick one is the 40 vial the common one or do people use 15
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quick one coming off semaglutide, is there a conversion or do i restart at 2.5
the switch felt like a step down at first and then caught up around week 22
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the 2 vial in 1ml gives 8mg/ml which puts 2.5 on 15 units, nice round numbers
the switch felt like a step down at first and then caught up around week 20, for what its worth
how many weeks at 7.5 before you knew it was enough
i sat at 7.5 for 19 months and never needed more, which is where the folklore comes from
15 is the top
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the sweet spot argument is really about effect per side effect, not a magic number
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dual agonist, GIP as well as GLP-1, thats the whole difference in one line
folklore probably
my PeptideMeter result on a TFC vial came in at 99 which is why i keep buying from them
if youre coming off semaglutide the honest answer is start low and find out, theres no table
is there a reason to titrate slower than the four week schedule
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GI was noticeably easier for me than semaglutide at what felt like the same appetite effect
the 2.5 to 5 step was the roughest one for me and everything after was easier, take that with a pinch of salt
unrelated but i went to 15 and came back to 10, more suppression wasnt more useful for me
Reminder set. I will post here in 4 days.
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sharps_bin_sidunrelated but i went to 15 and came back to 10, more suppression wasnt more useful for…
there is no clean conversion between the two, anyone giving you a ratio is guessing
SURMOUNT is weight
coming back to this anyone got a 4 recon they like for the 10 vials
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restarted at 2.5 after 25 months off and the first two doses reminded me why titration exists
*Janoshik not the other one
12 did nothing extra over 10 for me and that still holds a year later
i went to 15 and came back to 10, more suppression wasnt more useful for me
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plateaued at 28 weeks the same way i did on semaglutide, so i doubt its compound specific
switched last year
the GIP explanation for easier nausea is plausible and i still treat it as a story not a fact
£185 for a 40 vial is roughly what ive paid for the last year
5 did nothing
at 15 the GI came back for me, so my easier profile claim only applies below that
licensed top is 15 weekly, past that is not a licensed dose and nobody here can tell you what it does
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