vialroom

#tirzepatide 2026-01-03

Saturday17 messages6 participantstimes are UTC
Highlights from this day
  • taper_or_not — the switch felt like a step down at first and then caught up around week 21 14:27
  • VialBot — Verification log updated: HJ — evidence added, status unchanged. 14:30
  • vat_on_import — ok so there is no clean conversion between the two, anyone giving you a ratio is guessing, happy to be corrected 15:09
  • taper_or_not — SURMOUNT-OSA was the sleep apnoea trial and it is not a weight headline however its quoted 16:40

the switch felt like a step down at first and then caught up around week 21

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QH

plateaued at 33 weeks the same way i did on semaglutide, so i doubt its compound specific

VB

Verification log updated: HJ — evidence added, status unchanged.

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TT

went back to semaglutide after 8 months because the cost difference mattered more than the GI

does the appetite effect feel different or just stronger

TT

the two compounds arent interchangeable week for week even if the effect ends up similar

VO

ok so there is no clean conversion between the two, anyone giving you a ratio is guessing, happy to be corrected

VO

GI was noticeably easier for me than semaglutide at what felt like the same appetite effect

restarted at 2.5 after 15 months off and the first two doses reminded me why titration exists

TO

SURMOUNT-OSA was the sleep apnoea trial and it is not a weight headline however its quoted

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