7.5 gang
| Trial schedule | What most people here do | |
|---|---|---|
| Step interval | 4 weeks, fixed | 4-12 weeks, on symptoms |
| Holding | protocol deviation | normal and expected |
| Top dose | reached by design | often never reached |
| Coming down | not studied | common at maintenance |
#tirzepatide 2025-09-24
Wednesday30 messages6 participantstimes are UTC
Highlights from this day
im at 0.25 and thinking about 2.5, did anyone gain anything from that step
10 was enough
right so if youre coming off semaglutide the honest answer is start low and find out, theres no table
how did people handle the 2.5 to 5 jump
15 is the top
while im here no gap when i switched, took the last semaglutide dose and started this a week later
switched from 0.5 semaglutide and started at 2.5, took the slow route, never regretted it
at 1 my appetite is gone entirely, did anyone go down rather than up
did anybody switch back to semaglutide after trying this
at 15 the GI came back for me, so my easier profile claim only applies below that
held 10 for 12 months and lost 8kg over that stretch, slow and boring and fine
there is no clean conversion between the two, anyone giving you a ratio is guessing
is SURMOUNT-OSA the sleep apnoea one
went back to semaglutide after 6 months because the cost difference mattered more than the GI
🎉1✅5
back after 21 months, do i restart at 2.5 or pick up near where i left off
🔥7😂15🙏12
SURMOUNT-OSA was the sleep apnoea trial and it is not a weight headline however its quoted
quick one the switch felt like a step down at first and then caught up around week 14
40 units of a 2 solution is a lot of volume and i check that one twice every single time
while im here the 2.5 to 5 step was the roughest one for me and everything after was easier
anyone got a 2.5 recon they like for the 20 vials
switched last year
does the appetite effect feel different or just stronger
€240 for a 30 vial is roughly what ive paid for the last year
is 7.5 really the sweet spot or is that just channel folklore
📉12
is the 5 vial the common one or do people use 40
the 5 vial in 2ml gives 8mg/ml which puts 1.7 on 50 units, nice round numbers, happy to be corrected
the sweet spot thing is survivorship, the people it worked for stayed and said so
easier gi for me
wren_weighs_inquick one the switch felt like a step down at first and then caught up around week 14…
12 did nothing extra over 10 for me and that still holds a year later, n of 1 obviously
[edited]the trials titrated every four weeks to a target, most people here stop at whatever works
GIP plus GLP-1