vialroom

#tirzepatide 2025-08-12

Tuesday24 messages6 participantstimes are UTC
Highlights from this day
  • cricket_or_footy — dual agonist, GIP as well as GLP-1, thats the whole difference in one line 18:45
  • cricket_or_footy — at 15 the GI came back for me, so my easier profile claim only applies below that 18:46
  • tga_notice — follow up the trials titrated every four weeks to a target, most people here stop at whatever works 21:00
  • gus_charts — licensed top is 15 weekly, past that is not a licensed dose and nobody here can tell you what it does 21:10

im at 5 and thinking about 10, did anyone gain anything from that step

same plateau here

SURMOUNT is weight

GC

whats the plateau pattern here, same as semaglutide or different

GG

at 1 my appetite is gone entirely, did anyone go down rather than up

the switch felt like a step down at first and then caught up around week 27

10 was enough

whats the top licensed dose, 15 or does it go higher

dual agonist, GIP as well as GLP-1, thats the whole difference in one line

📈1👀1

at 15 the GI came back for me, so my easier profile claim only applies below that

🔥2
FT

no gap when i switched, took the last semaglutide dose and started this a week later

TN

back after 24 months, do i restart at 2.5 or pick up near where i left off

TN

SURMOUNT-1 versus SURPASS-2, which one was the weight trial

TN

no clean conversion

Trial scheduleWhat most people here do
Step interval4 weeks, fixed4-12 weeks, on symptoms
Holdingprotocol deviationnormal and expected
Top dosereached by designoften never reached
Coming downnot studiedcommon at maintenance
FT

did anyone find the GI easier than semaglutide at an equivalent effect

TN

follow up the trials titrated every four weeks to a target, most people here stop at whatever works

TN

plateaued at 5 weeks the same way i did on semaglutide, so i doubt its compound specific

GC

is the sweet spot argument about effect or about side effects

licensed top is 15 weekly, past that is not a licensed dose and nobody here can tell you what it does

👀8