unrelated but if youre coming off semaglutide the honest answer is start low and find out, theres no table
#tirzepatide 2025-07-23
Wednesday44 messages8 participantstimes are UTC
Highlights from this day
- retention_time — restarted at 2.5 after 10 months off and the first two doses reminded me why titration exists 22:00
- retention_time — ok so no gap when i switched, took the last semaglutide dose and started this a week later 22:01
- impersonator_ip — anyone got a 8 recon they like for the 40 vials 22:13
- retention_time — 12 did nothing extra over 10 for me and that still holds a year later 22:22
- impersonator_ip — whats the top licensed dose, 15 or does it go higher 22:33
i went to 15 and came back to 10, more suppression wasnt more useful for me
im at 0.25 and thinking about 1, did anyone gain anything from that step
restarted at 2.5 after 10 months off and the first two doses reminded me why titration exists
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ok so no gap when i switched, took the last semaglutide dose and started this a week later
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no clean conversion
plateaued at 15 weeks the same way i did on semaglutide, so i doubt its compound specific
anyone got a 8 recon they like for the 40 vials
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how long before the dual thing was noticeable to you
update on the earlier thing dual agonist, GIP as well as GLP-1, thats the whole difference in one line
is the sweet spot argument about effect or about side effects
anyone tracked whether the GI difference held at the top doses
janoshik-kp-0925.pdf
2 pages · 912 KB · not retained in the public archive
12 did nothing extra over 10 for me and that still holds a year later
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is there a reason to titrate slower than the four week schedule
easier gi for me
the sweet spot argument is really about effect per side effect, not a magic number
whats the top licensed dose, 15 or does it go higher
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while im here did anyone find the GI easier than semaglutide at an equivalent effect
why does everyone talk about 7.5 and not 10
40 units of a 2.5 solution is a lot of volume and i check that one twice every single time
15 is the top
folklore probably
the 40 vial in 5ml gives 4mg/ml which puts 5 on 40 units, nice round numbers
switched from 2.5 semaglutide and started at 2.5, took the slow route, never regretted it
how did people handle the 2.5 to 5 jump
same plateau here
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retention_timerestarted at 2.5 after 10 months off and the first two doses reminded me why titration…
went back to semaglutide after 10 months because the cost difference mattered more than the GI
SURMOUNT is weight
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checked the units twice
did anybody switch back to semaglutide after trying this
my Janoshik result on a QYB vial came in at 99.4 which is why i keep buying from them
follow up the two compounds arent interchangeable week for week even if the effect ends up similar
GIP plus GLP-1
there is no clean conversion between the two, anyone giving you a ratio is guessing
GI was noticeably easier for me than semaglutide at what felt like the same appetite effect
whats the plateau pattern here, same as semaglutide or different
[edited]start low anyway
switched last year
10 was enough
SURMOUNT-OSA was the sleep apnoea trial and it is not a weight headline however its quoted
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anyone stopped at 10 and stayed there for months
coming back to this is the 5 vial the common one or do people use 2
the 2.5 to 5 step was the roughest one for me and everything after was easier