#tirzepatide 2025-07-15

Tuesday13 messages4 participantstimes are UTC

Highlights from this day

comment_fatigue — restarted at 2.5 after 23 months off and the first two doses reminded me why titration exists 17:18
spreadsheet_stu — switched from 7.5 semaglutide and started at 2.5, took the slow route, never regretted it 17:22
thirty_min_wait — SURMOUNT-OSA was the sleep apnoea trial and it is not a weight headline however its quoted 17:38

changed my mind about needing 15, i was chasing a number rather than an outcome

plateaued at 29 weeks the same way i did on semaglutide, so i doubt its compound specific

restarted at 2.5 after 23 months off and the first two doses reminded me why titration exists

🧪3💀8

is 7.5 really the sweet spot or is that just channel folklore

switched from 7.5 semaglutide and started at 2.5, took the slow route, never regretted it

wk 1-4    2.5mg
wk 5-8    5.0mg
wk 9-20   7.5mg   <- stayed here
wk 21-24  10.0mg  (no extra benefit for me)
wk 25+    7.5mg   (came back down)

🤝8

checked the units twice

no gap when i switched, took the last semaglutide dose and started this a week later

SURMOUNT-OSA was the sleep apnoea trial and it is not a weight headline however its quoted

im at 10 and thinking about 7.5, did anyone gain anything from that step

switched last year

did anyone go past 15 and was there any point to it

GIP plus GLP-1

there is no clean conversion between the two, anyone giving you a ratio is guessing