licensed top is 15 weekly, past that is not a licensed dose and nobody here can tell you what it does
#tirzepatide 2025-07-12
Saturday41 messages7 participantstimes are UTC
Highlights from this day
- meal_prep_mick — €120 for a 30 vial is roughly what ive paid for the last year 12:54
- noct.titrate — coming off semaglutide, is there a conversion or do i restart at 2.5 12:55
- noct.titrate — right so i went to 15 and came back to 10, more suppression wasnt more useful for me 14:15
- madrid_mg — no gap when i switched, took the last semaglutide dose and started this a week later 16:10
i argued the sweet spot was nonsense and then spent 23 months at 7.5 not needing more
$120 for a 2 vial is roughly what ive paid for the last year
restarted at 2.5 after 18 months off and the first two doses reminded me why titration exists
went back to semaglutide after 21 months because the cost difference mattered more than the GI
the two compounds arent interchangeable week for week even if the effect ends up similar
at 12 my appetite is gone entirely, did anyone go down rather than up
the 2.5 to 5 step was the roughest one for me and everything after was easier
dual agonist, GIP as well as GLP-1, thats the whole difference in one line
quick one 12 did nothing extra over 10 for me and that still holds a year later, for what its worth
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the GIP explanation for easier nausea is plausible and i still treat it as a story not a fact
GIP plus GLP-1
5 was where i first noticed it properly, 2.5 did almost nothing for me
switched last year
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if youre coming off semaglutide the honest answer is start low and find out, theres no table
plateaued at 2 weeks the same way i did on semaglutide, so i doubt its compound specific, for what its worth
slightly off topic but there is no clean conversion between the two, anyone giving you a ratio is guessing
GI was noticeably easier for me than semaglutide at what felt like the same appetite effect
SURMOUNT was the weight programme and SURPASS was diabetes, thats the split people mix up
easier gi for me
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identity_shiftrestarted at 2.5 after 18 months off and the first two doses reminded me why titration…
changed my mind about needing 15, i was chasing a number rather than an outcome
at 0.5 my appetite went completely and i dropped back a step, eating nothing isnt a win
held 10 for 9 months and lost 33kg over that stretch, slow and boring and fine
[edited]my VendorInvestigate result on a QST vial came in at 97.4 which is why i keep buying from them, happy to be corrected
coming back to this how many weeks at 7.5 before you knew it was enough
€120 for a 30 vial is roughly what ive paid for the last year
coming off semaglutide, is there a conversion or do i restart at 2.5
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the GI difference held for me right up to 15, which isnt what a couple of people here found
10 was enough
switched from 7.5 semaglutide and started at 2.5, took the slow route, never regretted it
same plateau here
the switch felt like a step down at first and then caught up around week 6, ill dig out the number
sorry to jump in the 2 vial in 1ml gives 5mg/ml which puts 15 on 40 units, nice round numbers
right so i went to 15 and came back to 10, more suppression wasnt more useful for me
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5 did nothing
i sat at 7.5 for 18 months and never needed more, which is where the folklore comes from, still working it out
titrate slow
i log everything and my appetite curve looks flatter across the week than my semaglutide log did
no gap when i switched, took the last semaglutide dose and started this a week later
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the 2.5 to 5 step was the roughest one for me and everything after was easier
does switching from semaglutide need a gap or do you just start