5 did nothing
🔥5
#tirzepatide 2025-05-16
Friday28 messages5 participantstimes are UTC
Highlights from this day
- meal_prep_mick — at 15 the GI came back for me, so my easier profile claim only applies below that, your mileage will differ 12:09
- vacuum_vic — is the 15 vial the common one or do people use 20 13:56
- gip_glp_gil — the sweet spot argument is really about effect per side effect, not a magic number 15:17
checked the units twice
is the sweet spot argument about effect or about side effects
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dual agonist, GIP as well as GLP-1, thats the whole difference in one line
restarted at 2.5 after 8 months off and the first two doses reminded me why titration exists
SURMOUNT was the weight programme and SURPASS was diabetes, thats the split people mix up
how did people handle the 2.5 to 5 jump
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7.5 gang
start low anyway
SURMOUNT is weight
the 20 vial in 3ml gives 5mg/ml which puts 1 on 20 units, nice round numbers
update on the earlier thing did anybody switch back to semaglutide after trying this
⚠️15
does the GIP arm actually explain the easier nausea or is that hand waving
vial-h-2814-front.png
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at 15 the GI came back for me, so my easier profile claim only applies below that, your mileage will differ
coa-b-0114.pdf
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12 did nothing extra over 10 for me and that still holds a year later
5 was where i first noticed it properly, 2.5 did almost nothing for me
titrate slow
10 was enough
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plateaued at 32 weeks the same way i did on semaglutide, so i doubt its compound specific
GI was noticeably easier for me than semaglutide at what felt like the same appetite effect
i went to 15 and came back to 10, more suppression wasnt more useful for me
*PeptideMeter not the other one
15 is the top
is the 15 vial the common one or do people use 20
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is SURMOUNT-OSA the sleep apnoea one
the sweet spot argument is really about effect per side effect, not a magic number
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GIP plus GLP-1
[edited]anyone tracked whether the GI difference held at the top doses
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my Janoshik result on a CPC vial came in at 96.8 which is why i keep buying from them
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the sweet spot thing is survivorship, the people it worked for stayed and said so, n of 1 obviously