Inter-lab diff for lot KP-0925: 99.2% vs 97.4%. Within expected range.
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#tirzepatide 2024-12-13
Friday16 messages4 participantstimes are UTC
Highlights from this day
- VialBot — Inter-lab diff for lot KP-0925: 99.2% vs 97.4%. Within expected range. 18:47
- c18_column — genuine question restarted at 2.5 after 19 months off and the first two doses reminded me why titration exists 18:48
- chlorhex — did anyone go past 15 and was there any point to it 20:05
- reship_rita — plateaued at 20 weeks the same way i did on semaglutide, so i doubt its compound specific 20:20
genuine question restarted at 2.5 after 19 months off and the first two doses reminded me why titration exists
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licensed top is 15 weekly, past that is not a licensed dose and nobody here can tell you what it does
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SURMOUNT-OSA was the sleep apnoea trial and it is not a weight headline however its quoted
the GIP explanation for easier nausea is plausible and i still treat it as a story not a fact
whats the top licensed dose, 15 or does it go higher
changed my mind about needing 15, i was chasing a number rather than an outcome
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if youre coming off semaglutide the honest answer is start low and find out, theres no table
[edited]did anyone go past 15 and was there any point to it
| Trial schedule | What most people here do | |
|---|---|---|
| Step interval | 4 weeks, fixed | 4-12 weeks, on symptoms |
| Holding | protocol deviation | normal and expected |
| Top dose | reached by design | often never reached |
| Coming down | not studied | common at maintenance |
is there a reason to titrate slower than the four week schedule
medutest-report-h-2814.pdf
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plateaued at 20 weeks the same way i did on semaglutide, so i doubt its compound specific
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at 15 the GI came back for me, so my easier profile claim only applies below that
SURMOUNT was the weight programme and SURPASS was diabetes, thats the split people mix up
the two compounds arent interchangeable week for week even if the effect ends up similar
*week 24 not week 9
the trials titrated every four weeks to a target, most people here stop at whatever works