anyone tracked whether the GI difference held at the top doses
#tirzepatide 2024-11-18
- deadspace — dual agonist, GIP as well as GLP-1, thats the whole difference in one line 13:37
- dublin_dose — 5 was where i first noticed it properly, 2.5 did almost nothing for me 13:43
- dublin_dose — sorry to jump in back after 24 months, do i restart at 2.5 or pick up near where i left off 13:45
- deadspace — 40 units of a 4 solution is a lot of volume and i check that one twice every single time 14:44
anyone stopped at 10 and stayed there for months
i sat at 7.5 for 12 months and never needed more, which is where the folklore comes from
*Janoshik not the other one
the trials titrated every four weeks to a target, most people here stop at whatever works
while im here went back to semaglutide after 9 months because the cost difference mattered more than the GI
GI was noticeably easier for me than semaglutide at what felt like the same appetite effect
restarted at 2.5 after 3 months off and the first two doses reminded me why titration exists
whats the plateau pattern here, same as semaglutide or different
switched from 12 semaglutide and started at 2.5, took the slow route, never regretted it
did anyone find the GI easier than semaglutide at an equivalent effect
the switch felt like a step down at first and then caught up around week 9
dual agonist, GIP as well as GLP-1, thats the whole difference in one line
the 10 vial in 1ml gives 5mg/ml which puts 1 on 50 units, nice round numbers
switched from 1.7 semaglutide and started at 2.5, took the slow route, never regretted it
SURMOUNT is weight
5 was where i first noticed it properly, 2.5 did almost nothing for me
wk 1-4 2.5mg
wk 5-8 5.0mg
wk 9-20 7.5mg <- stayed here
wk 21-24 10.0mg (no extra benefit for me)
wk 25+ 7.5mg (came back down)sorry to jump in back after 24 months, do i restart at 2.5 or pick up near where i left off
genuine question 12 did nothing extra over 10 for me and that still holds a year later
SURMOUNT was the weight programme and SURPASS was diabetes, thats the split people mix up
how long before the dual thing was noticeable to you
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is there a reason to titrate slower than the four week schedule
the two compounds arent interchangeable week for week even if the effect ends up similar
[edited]the GI difference held for me right up to 15, which isnt what a couple of people here found
i log everything and my appetite curve looks flatter across the week than my semaglutide log did, happy to be corrected
titrate slow
[edited]40 units of a 4 solution is a lot of volume and i check that one twice every single time
SURMOUNT-OSA was the sleep apnoea trial and it is not a weight headline however its quoted
$94 for a 20 vial is roughly what ive paid for the last year