€185 for a 2 vial is roughly what ive paid for the last year
#tirzepatide 2024-10-26
Saturday49 messages9 participantstimes are UTC
Highlights from this day
- gip_glp_gil — whats the plateau pattern here, same as semaglutide or different 13:03
- eight_mm — at 0.5 my appetite went completely and i dropped back a step, eating nothing isnt a win changed my mind about needing 15, i was chasing a number rather than an outcome 14:52
- comment_fatigue — does the appetite effect feel different or just stronger 15:53
titrate slow
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slightly off topic but anyone got a 4 recon they like for the 20 vials
whats the plateau pattern here, same as semaglutide or different
| Trial schedule | What most people here do | |
|---|---|---|
| Step interval | 4 weeks, fixed | 4-12 weeks, on symptoms |
| Holding | protocol deviation | normal and expected |
| Top dose | reached by design | often never reached |
| Coming down | not studied | common at maintenance |
i sat at 7.5 for 4 months and never needed more, which is where the folklore comes from, ill dig out the number
checked the units twice
dual agonist, GIP as well as GLP-1, thats the whole difference in one line, i have it written down somewhere
the sweet spot thing is survivorship, the people it worked for stayed and said so, i have it written down somewhere
[edited]SURMOUNT-1 versus SURPASS-2, which one was the weight trial
is there a reason to titrate slower than the four week schedule
*VendorInvestigate not the other one
if youre coming off semaglutide the honest answer is start low and find out, theres no table
right so switched from 2.4 semaglutide and started at 2.5, took the slow route, never regretted it
coming off semaglutide, is there a conversion or do i restart at 2.5
why does everyone talk about 7.5 and not 10
while im here the sweet spot argument is really about effect per side effect, not a magic number
Assay note: GL Biochem lot C-4402 reported at 96.8% of label content.
7.5 gang
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changed my mind about needing 15, i was chasing a number rather than an outcome, i could be wrong
held 10 for 4 months and lost 16kg over that stretch, slow and boring and fine
no clean conversion
no gap when i switched, took the last semaglutide dose and started this a week later
5 was where i first noticed it properly, 2.5 did almost nothing for me
i argued the sweet spot was nonsense and then spent 22 months at 7.5 not needing more
[edited]at 15 the GI came back for me, so my easier profile claim only applies below that
did anyone go past 15 and was there any point to it
at 0.5 my appetite went completely and i dropped back a step, eating nothing isnt a win
changed my mind about needing 15, i was chasing a number rather than an outcome
SURMOUNT was the weight programme and SURPASS was diabetes, thats the split people mix up
no_appetite_niaif youre coming off semaglutide the honest answer is start low and find out, theres no…
licensed top is 15 weekly, past that is not a licensed dose and nobody here can tell you what it does
easier gi for me
is 7.5 really the sweet spot or is that just channel folklore
does switching from semaglutide need a gap or do you just start
the GI difference held for me right up to 15, which isnt what a couple of people here found
did anyone find the GI easier than semaglutide at an equivalent effect
the two compounds arent interchangeable week for week even if the effect ends up similar
does the appetite effect feel different or just stronger
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i went to 15 and came back to 10, more suppression wasnt more useful for me, still working it out
restarted at 2.5 after 2 months off and the first two doses reminded me why titration exists
follow up there is no clean conversion between the two, anyone giving you a ratio is guessing
is the sweet spot argument about effect or about side effects
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did going from 0.25 semaglutide to 5 of this feel like a step down for anyone
15 is the top
ok so plateaued at 30 weeks the same way i did on semaglutide, so i doubt its compound specific
im at 15 and thinking about 0.25, did anyone gain anything from that step
my PeptideMeter result on a GL Biochem vial came in at 99.2 which is why i keep buying from them
folklore probably
40 units of a 8 solution is a lot of volume and i check that one twice every single time
switched last year
went back to semaglutide after 17 months because the cost difference mattered more than the GI