vialroom

#tirzepatide 2024-06-16

Sunday31 messages9 participantstimes are UTC
Highlights from this day
  • private_script_pri — the trials titrated every four weeks to a target, most people here stop at whatever works 12:24
  • aliquot_ada — 5 was where i first noticed it properly, 2.5 did almost nothing for me 13:10
  • aliquot_ada — right so did going from 0.25 semaglutide to 5 of this feel like a step down for anyone 14:10
  • marrow.mod — follow up SURMOUNT-OSA was the sleep apnoea trial and it is not a weight headline however its quoted 16:11
  • slow.taper — ok so did anyone go past 15 and was there any point to it 17:02
PM

plateaued at 6 weeks the same way i did on semaglutide, so i doubt its compound specific

PS

the trials titrated every four weeks to a target, most people here stop at whatever works

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TT

slightly off topic but im at 7.5 and thinking about 0.25, did anyone gain anything from that step

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AA

5 was where i first noticed it properly, 2.5 did almost nothing for me

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PM

i log everything and my appetite curve looks flatter across the week than my semaglutide log did

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AA

went back to semaglutide after 15 months because the cost difference mattered more than the GI

switched last year

AA

right so did going from 0.25 semaglutide to 5 of this feel like a step down for anyone

❤️112

SURMOUNT is weight

wk 1-4    2.5mg
wk 5-8    5.0mg
wk 9-20   7.5mg   <- stayed here
wk 21-24  10.0mg  (no extra benefit for me)
wk 25+    7.5mg   (came back down)
PM

the 40 vial in 2ml gives 4mg/ml which puts 10 on 5 units, nice round numbers

HH

slightly off topic but i went to 15 and came back to 10, more suppression wasnt more useful for me

👍3
PM

the 2.5 to 5 step was the roughest one for me and everything after was easier

HH

restarted at 2.5 after 20 months off and the first two doses reminded me why titration exists

MM

no gap when i switched, took the last semaglutide dose and started this a week later

VB

Archive lookup: taper_tess first appears in this channel on 2024-01-01.

TT

GI was noticeably easier for me than semaglutide at what felt like the same appetite effect

MM

if youre coming off semaglutide the honest answer is start low and find out, theres no table

MM

does the GIP arm actually explain the easier nausea or is that hand waving

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MM

follow up SURMOUNT-OSA was the sleep apnoea trial and it is not a weight headline however its quoted

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NT

SURMOUNT was the weight programme and SURPASS was diabetes, thats the split people mix up

TT

is 7.5 really the sweet spot or is that just channel folklore

at 2.5 my appetite went completely and i dropped back a step, eating nothing isnt a win

ST

anyone tracked whether the GI difference held at the top doses

ok so did anyone go past 15 and was there any point to it

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17:43marrow.mod pinned a message