the sweet spot argument is really about effect per side effect, not a magic number, ill dig out the number
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#tirzepatide 2024-06-07
Friday29 messages8 participantstimes are UTC
Highlights from this day
- tenpence — follow up if youre coming off semaglutide the honest answer is start low and find out, theres no table 20:54
- VialBot — Inter-lab diff for lot G-0641: 98.1% vs 99.4%. Within expected range. 20:57
- reship_rita — the two compounds arent interchangeable week for week even if the effect ends up similar 21:35
- tare_weight — did anyone find the GI easier than semaglutide at an equivalent effect 22:02
- tare_weight — is the 2 vial the common one or do people use 30 22:05
plateaued at 19 weeks the same way i did on semaglutide, so i doubt its compound specific
5 did nothing
no clean conversion
restarted at 2.5 after 11 months off and the first two doses reminded me why titration exists
the GI difference held for me right up to 15, which isnt what a couple of people here found
follow up does the appetite effect feel different or just stronger
Inter-lab diff for lot B-0329: 96.8% vs 99%. Within expected range.
coming off semaglutide, is there a conversion or do i restart at 2.5
switched from 1 semaglutide and started at 2.5, took the slow route, never regretted it
titrate slow
at 1 my appetite is gone entirely, did anyone go down rather than up
follow up if youre coming off semaglutide the honest answer is start low and find out, theres no table
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Inter-lab diff for lot G-0641: 98.1% vs 99.4%. Within expected range.
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SURMOUNT-1 versus SURPASS-2, which one was the weight trial
the 2.5 to 5 step was the roughest one for me and everything after was easier, i could be wrong
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the two compounds arent interchangeable week for week even if the effect ends up similar
wk 1-4 2.5mg
wk 5-8 5.0mg
wk 9-20 7.5mg <- stayed here
wk 21-24 10.0mg (no extra benefit for me)
wk 25+ 7.5mg (came back down)there is no clean conversion between the two, anyone giving you a ratio is guessing
why does everyone talk about 7.5 and not 10
ok so went back to semaglutide after 17 months because the cost difference mattered more than the GI, anyway
start low anyway
15 is the top
12 did nothing extra over 10 for me and that still holds a year later
did anyone find the GI easier than semaglutide at an equivalent effect
is the 2 vial the common one or do people use 30
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same plateau here
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i log everything and my appetite curve looks flatter across the week than my semaglutide log did
licensed top is 15 weekly, past that is not a licensed dose and nobody here can tell you what it does
held 10 for 10 months and lost 7kg over that stretch, slow and boring and fine