sample handling on your end absolutely affects it. draw cleanly, ship fast, do not let it sit warm, not advice obviously
#test-results 2025-10-29
Wednesday21 messages7 participantstimes are UTC
Highlights from this day
- rezept_rolf — log the boring results too. a channel that only records failures produces a false picture, ill dig out the number 19:56
- deamidation — 98.1 against a certificate of 96.8 is fine. the same supplier landing low four times in a row is a question 21:01
- area_percent — assay under label with good purity means you got less of the right thing. that is a fill problem, not a synthesis problem, for what its worth 21:38
i have never regretted spending the money on a test. i have regretted not testing twice
my sheet has 8 lots from TFC with a spread under a point, which is tight
thats within range
| Evidence | Counts? |
|---|---|
| Independent report, lot you bought, lot number legible | yes |
| Independent report, no lot number | no |
| Supplier certificate only | no |
| Screenshot of a report | no |
| Blinded pooled submission | yes, for the pool |
| A friend who said it was fine | no |
test it again
👀18💀13
log the boring results too. a channel that only records failures produces a false picture, ill dig out the number
🔥14📉11
whats the underfill rate people are actually seeing
one data point
nice result
does anyone log the negative results, the boring ones
sorry to jump in do the results in this channel skew because people test when suspicious
[edited]log the lot number
| Evidence | Counts? |
|---|---|
| Independent report, lot you bought, lot number legible | yes |
| Independent report, no lot number | no |
| Supplier certificate only | no |
| Screenshot of a report | no |
| Blinded pooled submission | yes, for the pool |
| A friend who said it was fine | no |
follow up anyone had a result they think was a lab error rather than a bad vial
📈6
log the boring ones
| Evidence | Counts? |
|---|---|
| Independent report, lot you bought, lot number legible | yes |
| Independent report, no lot number | no |
| Supplier certificate only | no |
| Screenshot of a report | no |
| Blinded pooled submission | yes, for the pool |
| A friend who said it was fine | no |
a supplier disputing a result is rare here and it has never gone well for the supplier
Assay note: Homopeptide lot B-0114 reported at 98.1% of label content.
Assay note: KP lot KP-0925 reported at 98.6% of label content.
98.1 against a certificate of 96.8 is fine. the same supplier landing low four times in a row is a question
👍17✅3
what interests me is when the gap goes the same direction every time. once is noise, three times is a pattern
assay under label with good purity means you got less of the right thing. that is a fill problem, not a synthesis problem, for what its worth
lot bought purity assay/label
A-2418 2025-03 99.1% 9.6 / 10mg
A-2601 2025-08 98.7% 9.8 / 10mg
B-0114 2026-01 99.3% 9.4 / 10mg
B-0329 2026-04 98.9% 9.9 / 10mg