a few hours at room temperature is almost certainly nothing. a week is a different conversation, not advice obviously
i left a reconstituted vial out overnight once, sent it for testing out of curiosity, it came back fine
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#storage-coldchain 2026-06-23
Tuesday42 messages6 participantstimes are UTC
Highlights from this day
- kelp_keeps — a few hours at room temperature is almost certainly nothing. a week is a different conversation, not advice obviously i left a reconstituted vial out overnight once,… 12:10
- kelp_keeps — for flying, hand luggage every time. the hold is not temperature controlled the way people assume, still working it out 12:36
- kelp_keeps — i have never had a lyophilised vial fail after a warm transit and i have had some bad ones 12:38
i left a reconstituted vial out overnight once, sent it for testing out of curiosity, it came back fine
buy a thermometer. mine reads 5.6 on the door and two degrees lower at the back, i have it written down somewhere
hotel minibars are frequently not cold enough. i take a thermometer, which is ridiculous and also correct
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do i need to worry about light exposure or is that overthinking
buy a thermometer
how do you keep it cold on a long drive in summer
for flying, hand luggage every time. the hold is not temperature controlled the way people assume, still working it out
mon 4.1 / door 7.2
tue 4.0 / door 7.8
wed 4.2 / door 6.9
thu 3.9 / door 7.4
fri 4.1 / door 8.1 <- shopping day
sat 4.3 / door 7.0
sun 4.0 / door 6.8🙏15⚠️3
i have never had a lyophilised vial fail after a warm transit and i have had some bad ones
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unopened and in-use in the same place is fine. just keep the in-use one where you can reach it
back of the fridge
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quick one the door swings four or five degrees every time somebody opens it. the back barely moves
while im here how cold is too cold, can it actually freeze in a normal fridge
i freeze aliquots and have had them test fine afterwards. others here would not do it and i understand why
lyophilised powder is genuinely robust. a warm transit is far less likely to matter than people fear
freezing reconstituted peptide is the one thing this channel has never agreed on, n of 1 obviously
gel packs
i keep everything at the back of the middle shelf, never the door
[edited]a cooler with two gel packs held under eight degrees for eleven hours on a drive
update from 4 months ago: replaced the fridge, temperature is stable, no more anxiety
the practical risk in winter shipping is freezing, and in summer it is heat. plan for the season you are in
sorry to jump in freeze thaw cycling is the risk, not one freeze. that is my read of it anyway
parcel sat in a hot mailbox for 7 hours, is it dead
freeze debate again
a liquid cold pack tells you it was above freezing, not that your vial cooked
what temperature does a domestic fridge door actually swing to
power cut with the door shut for a few hours is fine. a full fridge holds temperature surprisingly well
anyone had a vial visibly change after a warm transit
the vial that visibly changed after a warm transit was the one that had already been reconstituted
two to eight degrees. most domestic fridge doors are not in that range and people do not check
power cut for 6 hours, fridge stayed shut, am i fine
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if you are worried after a bad transit, test it. that is what the testing channels are for
i log the fridge temperature daily and the room has never let me forget it, for what its worth
i would bin it
i left it out overnight by accident, bin it or use it
coming back after 26 months, is the pinned storage table still current
right so is there a difference in stability between the compounds
hand luggage, i have it written down somewhere
best travel setup for 25 days away with vials
light exposure matters much less than temperature for these. i still keep them in the carton
*Janoshik not the other one
i would use it