vialroom

#storage-coldchain 2026-06-12

Friday33 messages9 participantstimes are UTC
Highlights from this day
  • VialBot — Recon calculator: 15mg in 0.5ml = 10mg/ml. 14:57
  • pinch_not_stretch — hotel minibars are frequently not cold enough. i take a thermometer, which is ridiculous and also correct 15:16
  • pinch_not_stretch — the door swings four or five degrees every time somebody opens it. the back barely moves 16:31
PN

i left a reconstituted vial out overnight once, sent it for testing out of curiosity, it came back fine, i think

VB

Recon calculator: 15mg in 0.5ml = 10mg/ml.

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PN

for the archive if you are worried after a bad transit, test it. that is what the testing channels are for, still working it out

hotel minibars are frequently not cold enough. i take a thermometer, which is ridiculous and also correct

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i freeze aliquots and have had them test fine afterwards. others here would not do it and i understand why

log it

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VB

Reminder for pinch_not_stretch: dose day is today. Set 7 days ago.

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PN

follow up the vial that visibly changed after a warm transit was the one that had already been reconstituted

FF

buy a thermometer. mine reads 6.2 on the door and two degrees lower at the back

PN

sorry to jump in coming back after 18 months, is the pinned storage table still current

anyone had a vial visibly change after a warm transit

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PN

the door swings four or five degrees every time somebody opens it. the back barely moves

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cold pack arrived completely liquid, does that mean anything

FM

genuine question how cold is too cold, can it actually freeze in a normal fridge

update from 3 months ago: replaced the fridge, temperature is stable, no more anxiety

FM

two to eight degrees. most domestic fridge doors are not in that range and people do not check

TO

lyophilised powder is genuinely robust. a warm transit is far less likely to matter than people fear
a cooler with two gel packs held under eight degrees for eleven hours on a drive

FM

i have never had a lyophilised vial fail after a warm transit and i have had some bad ones

FM

unopened and in-use in the same place is fine. just keep the in-use one where you can reach it

BR

a few hours at room temperature is almost certainly nothing. a week is a different conversation, thats just me

solution is not

[edited]

light exposure matters much less than temperature for these. i still keep them in the carton