slightly off topic but update from 4 months ago: replaced the fridge, temperature is stable, no more anxiety
#storage-coldchain 2026-04-18
Saturday44 messages10 participantstimes are UTC
Highlights from this day
- VialBot — Reminder for ring_size_down: dose day is today. Set 6 days ago. 21:13
- ring_size_down — anyone tested a vial before and after a bad transit 21:29
- juno_joins — a cooler with two gel packs held under eight degrees for eleven hours on a drive 22:42
- tenpence — for flying, hand luggage every time. the hold is not temperature controlled the way people assume 22:48
Reminder for ring_size_down: dose day is today. Set 6 days ago.
if you are worried after a bad transit, test it. that is what the testing channels are for
a cooler with two gel packs held under eight degrees for eleven hours on a drive
how cold is too cold, can it actually freeze in a normal fridge
update on the earlier thing a few hours at room temperature is almost certainly nothing. a week is a different conversation
do i need to worry about light exposure or is that overthinking
freeze debate again
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a liquid cold pack tells you it was above freezing, not that your vial cooked
anyone tested a vial before and after a bad transit
mon 4.1 / door 7.2
tue 4.0 / door 7.8
wed 4.2 / door 6.9
thu 3.9 / door 7.4
fri 4.1 / door 8.1 <- shopping day
sat 4.3 / door 7.0
sun 4.0 / door 6.8two to eight
i would use it
the vial that visibly changed after a warm transit was the one that had already been reconstituted
follow up light exposure matters much less than temperature for these. i still keep them in the carton
is a five pound fridge thermometer actually worth it
for flying, hand luggage every time. the hold is not temperature controlled the way people assume
power cut with the door shut for a few hours is fine. a full fridge holds temperature surprisingly well
the practical risk in winter shipping is freezing, and in summer it is heat. plan for the season you are in
right so i left it out overnight by accident, bin it or use it
what temperature does a domestic fridge door actually swing to
the door swings four or five degrees every time somebody opens it. the back barely moves
i left a reconstituted vial out overnight once, sent it for testing out of curiosity, it came back fine
test it
my fridge is 4.8
hand luggage
two to eight degrees. most domestic fridge doors are not in that range and people do not check
sorry to jump in how do you keep it cold on a long drive in summer
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i would bin it
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buy a thermometer
back of the fridge
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log it
nobody here can tell you a vial is safe. we can tell you what has and has not survived for us, happy to be corrected
a few hours at room temperature is almost certainly nothing. a week is a different conversation
solution is not
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buy a thermometer. mine reads 4 on the door and two degrees lower at the back
a cooler with two gel packs held under eight degrees for eleven hours on a drive
mon 4.1 / door 7.2
tue 4.0 / door 7.8
wed 4.2 / door 6.9
thu 3.9 / door 7.4
fri 4.1 / door 8.1 <- shopping day
sat 4.3 / door 7.0
sun 4.0 / door 6.8for flying, hand luggage every time. the hold is not temperature controlled the way people assume
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flying with vials, hand luggage or checked
update on the earlier thing reconstituted solution is the fragile part. that is where the cold chain actually earns its keep
On this day 4 years ago this channel logged 114 messages.
not the freezer
gel packs
lyophilised powder is genuinely robust. a warm transit is far less likely to matter than people fear
best travel setup for 23 days away with vials
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powder is robust
[edited]thats fine
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update on the earlier thing unopened and in-use in the same place is fine. just keep the in-use one where you can reach it